Concepedia

Hot Spot Engineering

Hot Spot Engineering is a protein engineering strategy that involves the identification and modification of critical interfacial residues, known as hot spots, to enhance or modulate the affinity, specificity, or stability of protein–protein interactions.

57

Publications

3.6K

Citations

293

Authors

92

Institutions

Publications per year

2017–2026

16

Parents

Publications

57

Creating, characterizing, and controlling chemistry with SERS hot spots

Samuel L. Kleinman, Renee R. Frontiera, Anne-Isabelle Henry et al. · Physical Chemistry Chemical Physics · 2012 · 724 citations

, , +17

Large-Scale Hot Spot Engineering for Quantitative SERS at the Single-Molecule Scale

Hung-Ying Chen, Meng-Hsien Lin, Chunyuan Wang et al. · Journal of the American Chemical Society · 2015 · 419 citations

, , +17

Hot-Spot Engineering in Polygonal Nanofinger Assemblies for Surface Enhanced Raman Spectroscopy

Fung Suong Ou, Min Hu, Ivan I. Naumov et al. · Nano Letters · 2011 · 208 citations

, , +17

HotSpot Wizard: a web server for identification of hot spots in protein engineering

Antonín Pavelka, Eva Chovancová, Jiřı́ Damborský · Nucleic Acids Research · 2009 · 198 citations · Full text

, , +17

The Microwave Drill

E. Jerby, V. Dikhtyar, O. Aktushev et al. · Science · 2002 · 176 citations

, , +12

1–5 of 57

Authors

293

  1. SK
    Suigen Kyoh

    Toshiba (Japan), Japan

    3 publications · 43 citations

    3

    h-index

  2. SK
    Sachiko Kobayashi

    Hokkaido University, Japan

    3 publications · 43 citations

    3

    h-index

  3. SI
    Soichi Inoue

    Toshiba (Japan), Japan

    3 publications · 43 citations

    3

    h-index

  4. HA
    Hesham Abdelbaset

    Minia University, Egypt

    2 publications · 63 citations

    2

    h-index

  5. XW
    Xiaoling Wu

    Beijing Normal University, China

    2 publications · 29 citations

    2

    h-index

1–5 of 293

Institutions

92

  1. Toshiba (Japan)

    Tokyo, Japan

    3 h-index

    17 publications

    243 citations

  2. South China University of Technology

    Guangzhou, China

    3 h-index

    10 publications

    183 citations

  3. Tsinghua University

    Beijing, China

    3 h-index

    6 publications

    234 citations

  4. Electronics and Telecommunications Research Institute

    Daejeon, South Korea

    3 h-index

    12 publications

    344 citations

  5. National Taiwan University

    Taipei, Taiwan

    2 h-index

    4 publications

    533 citations

  6. Shanghai Jiao Tong University

    Shanghai, China

    2 h-index

    6 publications

    189 citations

  7. Tianjin Chengjian University

    Tianjin, China

    2 h-index

    2 publications

    63 citations

  8. P.N. Lebedev Physical Institute of the Russian Academy of Sciences

    Moscow, Russia

    2 h-index

    5 publications

    94 citations

1–8 of 92

Venues

  1. 4

    h-index

  2. Applied Thermal Engineering

    3 publications · 64 citations

    3

    h-index

  3. The Journal of Physical Chemistry C

    2 publications · 58 citations

    2

    h-index

  4. Journal of the American Chemical Society

    JACS · 2 publications · 558 citations

    2

    h-index

  5. Nucleic Acids Research

    2 publications · 297 citations

    2

    h-index

1–5