Concepedia

Host Range Optimization

Host Range Optimization is a methodological strategy in expression vector design that systematically enhances the compatibility and efficiency of vector functionality across diverse host organisms by tailoring regulatory elements, replication origins, and selection markers to conserved or adaptable biological features of target hosts.

104

Publications

8.2K

Citations

475

Authors

191

Institutions

Publications per year

2017–2026

30

Parents

Publications

104

Deep Mutational Scanning of SARS-CoV-2 Receptor Binding Domain Reveals Constraints on Folding and ACE2 Binding

Tyler N. Starr, Allison J. Greaney, Sarah K. Hilton et al. · Cell · 2020 · 2.2K citations · Full text

, , +16

Spike protein recognition of mammalian ACE2 predicts the host range and an optimized ACE2 for SARS-CoV-2 infection

Junwen Luan, Yue Lu, Xiaolu Jin et al. · Biochemical and Biophysical Research Communications · 2020 · 407 citations · Full text

, , +17

Host Range and Cytopathogenicity of the Highly Attenuated MVA Strain of Vaccinia Virus: Propagation and Generation of Recombinant Viruses in a Nonhuman Mammalian Cell Line

Miles W. Carroll, Bernard Moss · Virology · 1997 · 330 citations

, , +15

Extending the Host Range of Listeria monocytogenes by Rational Protein Design

Thomas Wollert, Bastian Pasche, Maike Rochón et al. · Cell · 2007 · 214 citations · Full text

, , +16

Deep mutational scanning of SARS-CoV-2 receptor binding domain reveals constraints on folding and ACE2 binding

Tyler N. Starr, Allison J. Greaney, Sarah K. Hilton et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2020 · 183 citations · Full text

, , +16

1–5 of 104

Authors

475

  1. RG
    Rea Globus

    Tel Aviv University, Israel

    2 publications · 248 citations

    2

    h-index

  2. JE
    John E. Bowen

    University of Washington, United States

    2 publications · 2.4K citations

    2

    h-index

  3. JW
    Johannes Wittmann

    Leibniz Institute DSMZ – German Collection of Microorganisms and Cell Cultures, Germany

    2 publications · 61 citations

    2

    h-index

  4. IY
    Ido Yosef

    Tel Aviv University, Israel

    2 publications · 248 citations

    2

    h-index

  5. AJ
    Allison J. Greaney

    Fred Hutch Cancer Center, United States

    2 publications · 2.4K citations

    2

    h-index

1–5 of 475

Institutions

191

  1. University of Washington

    Seattle, United States

    6 h-index

    29 publications

    27K citations

  2. National Institute of Allergy and Infectious Diseases

    Bethesda, United States

    4 h-index

    11 publications

    1.3K citations

  3. Fred Hutch Cancer Center

    Seattle, United States

    3 h-index

    13 publications

    14.4K citations

  4. Fundación Seimc-Gesida

    Madrid, Spain

    2 h-index

    20 publications

    850 citations

  5. Tel Aviv University

    Tel Aviv, Israel

    2 h-index

    10 publications

    1.2K citations

  6. Universidade da Coruña

    A Coruña, Spain

    2 h-index

    9 publications

    414 citations

  7. Instituto de Salud Carlos III

    Madrid, Spain

    2 h-index

    10 publications

    425 citations

  8. Consejo Superior de Investigaciones Científicas

    Madrid, Spain

    2 h-index

    3 publications

    99 citations

1–8 of 191

Venues

  1. Journal of Virology

    JVI · 10 publications · 619 citations

    10

    h-index

  2. Virology

    9 publications · 761 citations

    9

    h-index

  3. Biological Control

    4 publications · 107 citations

    4

    h-index

  4. PubMed

    Repository · 3 publications · 81 citations

    3

    h-index

  5. Viruses

    3 publications · 210 citations

    3

    h-index

1–5