Five birds, one stone: Neutralization of α-hemolysin and 4 bi-component leukocidins of <i>Staphylococcus aureus</i> with a single human monoclonal antibody

Harald Rouha, Adriana Badarau, Zehra Visram, +21

mAbs

Medical MicrobiologyAntibioticsMicrobial PathogensMedicineImmunology +12

Improved Protection in a Rabbit Model of Community-Associated Methicillin-Resistant Staphylococcus aureus Necrotizing Pneumonia upon Neutralization of Leukocidins in Addition to Alpha-Hemolysin

Binh An Diep, Vien T. M. Le, Zehra Visram, +5

Antimicrobial Agents and Chemotherapy

ImmunologyRabbit ModelNecrotizing PneumoniaUsa300 Ca-mrsa StrainDrug Resistance +16

Endotoxin neutralization by an O-antigen specific monoclonal antibody: A potential novel therapeutic approach against<i>Klebsiella pneumoniae</i>ST258

Valéria Szijártó, Luis Miguel Guachalla, Katharina Hartl, +7

Virulence

Disarming <i>Staphylococcus aureus</i> from destroying human cells by simultaneously neutralizing six cytotoxins with two human monoclonal antibodies

Harald Rouha, Susanne Weber, Philipp Janesch, +8

Virulence

ε2-Phages Are Naturally Bred and Have a Vastly Improved Host Range in Staphylococcus aureus over Wild Type Phages

David Sáez Moreno, Zehra Visram, Michele Mutti, +10

Pharmaceuticals

Bactericidal Monoclonal Antibodies Specific to the Lipopolysaccharide O Antigen from Multidrug-Resistant Escherichia coli Clone ST131-O25b:H4 Elicit Protection in Mice

Valéria Szijártó, Luis Miguel Guachalla, Zehra Visram, +10

Antimicrobial Agents and Chemotherapy

Preventing lung pathology and mortality in rabbit Staphylococcus aureus pneumonia models with cytotoxin-neutralizing monoclonal IgGs penetrating the epithelial lining fluid

Lukas Stulik, Harald Rouha, Delphine Labrousse, +10

Scientific Reports

Immunological fingerprinting of group B streptococci: From circulating human antibodies to protective antigens

Andreas Meinke, Beatrice M. Senn, Zehra Visram, +15

Vaccine

VaccinationMedical MicrobiologyGroup B StreptococciPathogenesisImmunology +8

Natural Bred ε2-Phages Have an Improved Host Range and Virulence against Uropathogenic Escherichia coli over Their Ancestor Phages

Maria Loose, David Sáez Moreno, Michele Mutti, +8

Antibiotics

Selective sensitization of human neutrophils to LukGH mediated cytotoxicity by Staphylococcus aureus and IL-8

Philipp Janesch, Harald Rouha, Susanne Weber, +6

Journal of Infection