Concepedia

Hla-dm Function

HLA-DM Function is a molecular chaperone mechanism in antigen processing that catalyzes the exchange of peptides bound to MHC class II molecules by facilitating the removal of invariant chain-derived peptides and stabilizing the peptide-receptive state of MHC II for optimal antigen presentation.

151

Publications

10.8K

Citations

585

Authors

190

Institutions

Publications per year

2017–2026

9

Parents

Publications

151

HLA-DM induces clip dissociation from MHC class II αβ dimers and facilitates peptide loading

Lisa Denzin, Peter Cresswell · Cell · 1995 · 681 citations · Full text

, , +14

Mediation by HLA-DM of dissociation of peptides from HLA-DR

Victor S. Sloan, Patricia M. Cameron, Gene Porter et al. · Nature · 1995 · 544 citations

, , +6

An essential role for HLA–DM in antigen presentation by class II major histocompatibility molecules

Phillip Morris, Jeffrey A. Shaman, Michelle Attaya et al. · Nature · 1994 · 375 citations

, , +16

Enhanced Dissociation of HLA-DR-Bound Peptides in the Presence of HLA-DM

Dominique A. Weber, Brian D. Evavold, Peter E. Jensen · Science · 1996 · 323 citations

, , +17

HLA-DMA and -DMB genes are both required for MHC class II/peptide complex formation in antigen-presenting cells

Steven P. Fling, Donald Pious · Nature · 1994 · 271 citations

, , +16

1–5 of 151

Authors

585

  1. EM
    Elizabeth Mellins

    Stanford University, United States

    23 publications · 2K citations

    19

    h-index

  2. LD
    Lisa Denzin

    Memorial Sloan Kettering Cancer Center, United States

    12 publications · 1.7K citations

    11

    h-index

  3. LJ
    Lawrence J. Stern

    University of Massachusetts Chan Medical School, United States

    9 publications · 703 citations

    9

    h-index

  4. RB
    Robert Busch

    University of Minnesota, United States

    8 publications · 481 citations

    8

    h-index

  5. JT
    John Trowsdale

    University of Cambridge, United Kingdom

    8 publications · 836 citations

    8

    h-index

1–5 of 585

Institutions

190

  1. Stanford University

    Stanford, United States

    19 h-index

    104 publications

    5.6K citations

  2. Harvard University

    Cambridge, United States

    13 h-index

    37 publications

    3.6K citations

  3. Howard Hughes Medical Institute

    Chevy Chase, United States

    12 h-index

    40 publications

    5.2K citations

  4. German Cancer Research Center

    Heidelberg, Germany

    8 h-index

    31 publications

    2.9K citations

  5. Yale University

    New Haven, United States

    8 h-index

    33 publications

    3.4K citations

  6. The Netherlands Cancer Institute

    Amsterdam, The Netherlands

    7 h-index

    19 publications

    1.9K citations

  7. Dana-Farber Cancer Institute

    Boston, United States

    7 h-index

    29 publications

    3.5K citations

  8. University of Washington

    Seattle, United States

    7 h-index

    16 publications

    901 citations

1–8 of 190

Venues

  1. The Journal of Immunology

    JI · 48 publications · 1.8K citations

    30

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 11 publications · 758 citations

    11

    h-index

  3. Immunity

    9 publications · 1.3K citations

    9

    h-index

  4. European Journal of Immunology

    EJI · 8 publications · 241 citations

    8

    h-index

  5. Journal of Biological Chemistry

    JBC · 6 publications · 260 citations

    6

    h-index

1–5