Concepedia

Hla Loss

HLA Loss is a genetic alteration in tumor cells characterized by the downregulation or absence of human leukocyte antigen class I molecules, thereby impairing antigen presentation and enabling immune evasion.

310

Publications

23.7K

Citations

2.2K

Authors

603

Institutions

Publications per year

2017–2026

46

Variants

Human Leukocyte Antigen Loss

Parents

Publications

310

Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution

Nicholas McGranahan, Rachel Rosenthal, Crispin T. Hiley et al. · Cell · 2017 · 1.3K citations · Full text

, , +16

Risks of leukaemia and solid tumours in individuals with Down's syndrome

Henrik Hasle, Inge Clemmensen, Margareta Mikkelsen · The Lancet · 2000 · 896 citations

, , +12

Characterization of an Antigen That Is Recognized on a Melanoma Showing Partial HLA Loss by CTL Expressing an NK Inhibitory Receptor

Hideyuki Ikeda, Bernard Lethé, Frédéric Lehmann et al. · Immunity · 1997 · 772 citations · Full text

, , +16

Genetic Mechanisms of Immune Evasion in Colorectal Cancer

Catherine S. Grasso, Marios Giannakis, Daniel K. Wells et al. · Cancer Discovery · 2018 · 550 citations · Full text

, , +17

The Hemochromatosis Founder Mutation in HLA-H Disrupts β2-Microglobulin Interaction and Cell Surface Expression

John N. Feder, Zenta Tsuchihashi, Alivelu Irrinki et al. · Journal of Biological Chemistry · 1997 · 479 citations · Full text

, , +10

1–5 of 310

Authors

2.2K

  1. FG
    Federico Garrido

    Hospital Universitario Virgen de las Nieves, Spain

    46 publications · 2.9K citations

    31

    h-index

  2. FR
    Francisco Ruiz‐Cabello

    Hospital Universitario Virgen de las Nieves, Spain

    33 publications · 2.3K citations

    26

    h-index

  3. TC
    Teresa Cabrera

    Hospital Universitario Virgen de las Nieves, Spain

    20 publications · 1.3K citations

    18

    h-index

  4. SF
    Soldano Ferrone

    Massachusetts General Hospital, United States

    19 publications · 2K citations

    17

    h-index

  5. IM
    Isabel Maleno

    Hospital Universitario Virgen de las Nieves, Spain

    13 publications · 600 citations

    12

    h-index

1–5 of 2.2K

Institutions

603

  1. Hospital Universitario Virgen de las Nieves

    Granada, Spain

    31 h-index

    244 publications

    15.8K citations

  2. Universidad de Granada

    Granada, Spain

    26 h-index

    144 publications

    9.4K citations

  3. Leiden University Medical Center

    Leiden, The Netherlands

    22 h-index

    152 publications

    14.5K citations

  4. Heidelberg University

    Heidelberg, Germany

    12 h-index

    54 publications

    3.3K citations

  5. Leiden University

    Leiden, The Netherlands

    12 h-index

    51 publications

    5.1K citations

  6. Harvard University

    Cambridge, United States

    11 h-index

    50 publications

    4K citations

  7. National Cancer Institute

    Bethesda, United States

    11 h-index

    48 publications

    4.6K citations

  8. University of Washington

    Seattle, United States

    10 h-index

    37 publications

    8.3K citations

1–8 of 603

Venues

  1. International Journal of Cancer

    30 publications · 2.2K citations

    25

    h-index

  2. PubMed

    Repository · 33 publications · 1.5K citations

    24

    h-index

  3. Tissue Antigens

    20 publications · 1.1K citations

    17

    h-index

  4. Human Immunology

    16 publications · 585 citations

    13

    h-index

  5. Cancer Immunology Immunotherapy

    11 publications · 609 citations

    11

    h-index

1–5