Concepedia

Histone Modification Editing

Histone Modification Editing is a molecular intervention strategy that selectively alters covalent post-translational modifications on histone proteins to modulate chromatin structure and regulate gene expression without changing the underlying DNA sequence.

5

Publications

459

Citations

38

Authors

14

Institutions

Publications per year

2017–2026

4

Parents

Publications

5

Locus-specific editing of histone modifications at endogenous enhancers

Eric M. Mendenhall, Kaylyn E. Williamson, Deepak Reyon et al. · Nature Biotechnology · 2013 · 367 citations · Full text

, , +16

Targeted in vivo epigenome editing of H3K27me3

Hiroto Fukushima, Hiroyuki Takeda, Ryohei Nakamura · Epigenetics & Chromatin · 2019 · 36 citations · Full text

, , +17

A General Method to Edit Histone H3 Modifications on Chromatin Via Sortase‐Mediated Metathesis

Qingyun Yang, Yingxiao Gao, Xia Liu et al. · Angewandte Chemie International Edition · 2022 · 22 citations

, , +13

Allosteric regulation of protein 14-3-3ζ scaffold by small-molecule editing modulates histone H3 post-translational modifications

Yanjun Wan, Li‐Xi Liao, Yang Liu et al. · Theranostics · 2019 · 21 citations · Full text

, , +17

<i>upSET</i>, the <i>Drosophila</i> homologue of SET3, Is Required for Viability and the Proper Balance of Active and Repressive Chromatin Marks

Kyle A. McElroy, Youngsook L. Jung, Barry M. Zee et al. · G3 Genes Genomes Genetics · 2017 · 13 citations · Full text

, , +11

1–5 of 5

Authors

38

  1. MW
    Mingxuan Wu

    Harvard University, United States

    1 publications · 22 citations

    1

    h-index

  2. RN
    Ryohei Nakamura

    The University of Tokyo, Japan

    1 publications · 36 citations

    1

    h-index

  3. DR
    Deepak Reyon

    Harvard University, United States

    1 publications · 367 citations

    1

    h-index

  4. XZ
    Xiaowen Zhang

    China Medical University, China

    1 publications · 21 citations

    1

    h-index

  5. ZD
    Zhiyong Du

    Peking University, China

    1 publications · 21 citations

    1

    h-index

1–5 of 38

Institutions

14

  1. Center for Systems Biology

    Boston, United States

    2 h-index

    6 publications

    1.5K citations

  2. Harvard University

    Cambridge, United States

    2 h-index

    12 publications

    2.3K citations

  3. Center for Cancer Research

    Bethesda, United States

    1 h-index

    6 publications

    2.2K citations

  4. Zhejiang University

    Hangzhou, China

    1 h-index

    2 publications

    44 citations

  5. Massachusetts General Hospital

    Boston, United States

    1 h-index

    6 publications

    2.2K citations

  6. Qilu University of Technology

    Jinan, China

    1 h-index

    3 publications

    63 citations

  7. Peking University

    Beijing, China

    1 h-index

    15 publications

    315 citations

  8. Fudan University

    Shanghai, China

    1 h-index

    1 publications

    22 citations

1–8 of 14

Venues

  1. Epigenetics & Chromatin

    1 publications · 36 citations

    1

    h-index

  2. G3 Genes Genomes Genetics

    1 publications · 13 citations

    1

    h-index

  3. Angewandte Chemie International Edition

    1 publications · 22 citations

    1

    h-index

  4. Theranostics

    1 publications · 21 citations

    1

    h-index

  5. Nature Biotechnology

    1 publications · 367 citations

    1

    h-index

1–5