Concepedia

His Operon

His Operon is a genetic regulatory unit in prokaryotic molecular biology that consists of a cluster of coordinately controlled structural genes and associated cis-acting elements governing the biosynthesis of the amino acid histidine, distinguished from other operons by its specific repression mechanism in response to intracellular histidine levels.

161

Publications

8.6K

Citations

290

Authors

75

Institutions

Publications per year

2017–2026

1

Variants

Histidine Operon

Parents

Publications

161

Complete nucleotide sequence and identification of membrane components of the histidine transport operon of S. typhimurium

Chris Higgins, P. D. Haag, Kishiko Nikaido et al. · Nature · 1982 · 322 citations

, , +12

The Histidine Operon

B N Ames, Philip Hartman · Cold Spring Harbor Symposia on Quantitative Biology · 1963 · 285 citations

, , +14

Histidine regulatory mutants in Salmonella typhimurium

John R. Roth, Dora N. Antón, Philip Hartman · Journal of Molecular Biology · 1966 · 244 citations

, , +12

Guanosine 5'-diphosphate 3'-diphosphate (ppGpp): positive effector for histidine operon transcription and general signal for amino-acid deficiency.

John C. Stephens, S W Artz, B N Ames · Proceedings of the National Academy of Sciences · 1975 · 238 citations · Full text

, , +17

Classification of aminotransferase (C gene) mutants in the histidine operon

Harvey J. Whitfield, Robert G. Martin, Bruce N. Ames · Journal of Molecular Biology · 1966 · 220 citations

, , +11

1–5 of 161

Authors

290

  1. CB
    Carmelo B. Bruni

    Institute for Experimental Endocrinology and Oncology, Italy

    16 publications · 670 citations

    14

    h-index

  2. BN
    Bruce N. Ames

    University of California, Berkeley, United States

    14 publications · 1.3K citations

    13

    h-index

  3. FB
    Francesco Blasi

    Vita-Salute San Raffaele University, Italy

    10 publications · 362 citations

    10

    h-index

  4. RF
    Renato Fani

    University of Florence, Italy

    10 publications · 550 citations

    10

    h-index

  5. PH
    Philip Hartman

    Johns Hopkins University, United States

    10 publications · 970 citations

    10

    h-index

1–5 of 290

Institutions

75

  1. University of California, Berkeley

    Berkeley, United States

    20 h-index

    62 publications

    5.6K citations

  2. National Institute of Arthritis and Musculoskeletal and Skin Diseases

    Bethesda, United States

    20 h-index

    70 publications

    4.4K citations

  3. National Institutes of Health

    Bethesda, United States

    13 h-index

    47 publications

    2.2K citations

  4. Johns Hopkins University

    Baltimore, United States

    12 h-index

    22 publications

    1.9K citations

  5. University of Utah

    Salt Lake City, United States

    9 h-index

    21 publications

    1.2K citations

  6. University of Florence

    Florence, Italy

    8 h-index

    31 publications

    1.2K citations

  7. Institute for Experimental Endocrinology and Oncology

    Naples, Italy

    8 h-index

    29 publications

    1.4K citations

  8. University of California, Davis

    Davis, United States

    5 h-index

    15 publications

    472 citations

1–8 of 75

Venues

  1. Journal of Bacteriology

    JB · 38 publications · 1.6K citations

    25

    h-index

  2. Journal of Molecular Biology

    JMB · 27 publications · 2K citations

    21

    h-index

  3. Journal of Biological Chemistry

    JBC · 16 publications · 661 citations

    14

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 12 publications · 1.2K citations

    12

    h-index

  5. Molecular and General Genetics MGG

    13 publications · 312 citations

    12

    h-index

1–5