Concepedia

High-throughput Screening Libraries

High-Throughput Screening Libraries is a specialized collection of systematically organized chemical or biological compounds designed for rapid and automated evaluation of large numbers of molecules in parallel, distinguished by its integration with split-and-pool synthesis to enable the efficient exploration of vast combinatorial chemical space.

468

Publications

27.4K

Citations

3.2K

Authors

815

Institutions

Publications per year

2017–2026

164

Parents

Publications

468

Do Structurally Similar Molecules Have Similar Biological Activity?

Yvonne C. Martin, James L. Kofron, Linda Traphagen · Journal of Medicinal Chemistry · 2002 · 829 citations

, , +17

Metal complexes as a promising source for new antibiotics

Angelo Frei, Johannes Zuegg, Alysha G. Elliott et al. · Chemical Science · 2020 · 513 citations · Full text

, , +17

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond

Wesley C. Van Voorhis, John H. Adams, Roberto Adelfio et al. · PLoS Pathogens · 2016 · 448 citations · Full text

, , +11

Synthon-based ligand discovery in virtual libraries of over 11 billion compounds

Arman A. Sadybekov, Anastasiia Sadybekov, Yongfeng Liu et al. · Nature · 2021 · 433 citations · Full text

, , +14

Efficient Exploration of Chemical Space with Docking and Deep Learning

Yang Ying, Kun Yao, Matthew P. Repasky et al. · Journal of Chemical Theory and Computation · 2021 · 407 citations

, , +17

1–5 of 468

Authors

3.2K

  1. RH
    Ruili Huang

    National Institutes of Health, United States

    16 publications · 1K citations

    15

    h-index

  2. MX
    Menghang Xia

    National Institutes of Health, United States

    16 publications · 1K citations

    15

    h-index

  3. AS
    Anton Simeonov

    National Institutes of Health, United States

    11 publications · 817 citations

    10

    h-index

  4. JI
    James Inglese

    National Institutes of Health, United States

    8 publications · 447 citations

    8

    h-index

  5. AJ
    Ajit Jadhav

    National Institutes of Health, United States

    8 publications · 882 citations

    8

    h-index

1–5 of 3.2K

Institutions

815

  1. National Institutes of Health

    Bethesda, United States

    25 h-index

    241 publications

    14.4K citations

  2. National Center for Advancing Translational Sciences

    Rockville, United States

    20 h-index

    166 publications

    9.8K citations

  3. Harvard University

    Cambridge, United States

    15 h-index

    49 publications

    6.3K citations

  4. Scripps Research Institute

    San Diego, United States

    13 h-index

    58 publications

    5.5K citations

  5. Centre National de la Recherche Scientifique

    Paris, France

    11 h-index

    45 publications

    3K citations

  6. Novartis (Switzerland)

    Basel, Switzerland

    10 h-index

    30 publications

    1.5K citations

  7. Chinese Academy of Sciences

    Beijing, China

    9 h-index

    62 publications

    3.9K citations

  8. National Cancer Institute

    Bethesda, United States

    9 h-index

    60 publications

    5.1K citations

1–8 of 815

Venues

  1. SLAS DISCOVERY

    28 publications · 1.2K citations

    19

    h-index

  2. Journal of Chemical Information and Modeling

    JCIM · 20 publications · 1K citations

    16

    h-index

  3. Journal of Medicinal Chemistry

    16 publications · 1.8K citations

    15

    h-index

  4. Bioorganic & Medicinal Chemistry Letters

    14 publications · 623 citations

    14

    h-index

  5. Journal of Combinatorial Chemistry

    14 publications · 404 citations

    11

    h-index

1–5