Concepedia

High-plex Rna Imaging

High-Plex RNA Imaging is a spatial transcriptomics method that enables the simultaneous detection and localization of hundreds to thousands of RNA species within intact tissue sections using multiplexed molecular barcoding and sequential imaging rounds.

4

Publications

1.1K

Citations

57

Authors

6

Institutions

Publications per year

2017–2026

4

Parents

Publications

4

High-plex imaging of RNA and proteins at subcellular resolution in fixed tissue by spatial molecular imaging

Shanshan He, Ruchir Bhatt, Carl Brown et al. · Nature Biotechnology · 2022 · 778 citations

, , +17

The Spatial Landscape of Progression and Immunoediting in Primary Melanoma at Single-Cell Resolution

Ajit J. Nirmal, Zoltan Maliga, Tuulia Vallius et al. · Cancer Discovery · 2022 · 218 citations · Full text

, , +17

High-Plex Spatially Resolved RNA and Protein Detection Using Digital Spatial Profiling: A Technology Designed for Immuno-oncology Biomarker Discovery and Translational Research

Joseph Beechem · Methods in molecular biology · 2019 · 114 citations

, , +17

Multiomic analysis of human kidney disease identifies a tractable inflammatory and pro-fibrotic tubular cell phenotype

Maximilian Reck, David Baird, Stefan Veizades et al. · Nature Communications · 2025 · 30 citations · Full text

, , +17

HCR spectral imaging: 10-plex, quantitative, high-resolution RNA and protein imaging in highly autofluorescent samples

Samuel J. Schulte, Mark E. Fornace, John K. Hall et al. · Development · 2024 · 22 citations · Full text

, , +17

1–5 of 4

Authors

57

  1. JB
    Joseph Beechem

    Nanostring Technologies (United States), United States

    2 publications · 892 citations

    2

    h-index

  2. CA
    Connor A. Jacobson

    Harvard University, United States

    1 publications · 218 citations

    1

    h-index

  3. NA
    Niles A. Pierce

    California Institute of Technology, United States

    1 publications · 22 citations

    1

    h-index

  4. GS
    Grace Shin

    University of Southern California, United States

    1 publications · 22 citations

    1

    h-index

  5. YC
    Yu‐An Chen

    Harvard University, United States

    1 publications · 218 citations

    1

    h-index

1–5 of 57

Institutions

6

  1. Nanostring Technologies (United States)

    Seattle, United States

    2 h-index

    39 publications

    29.7K citations

  2. Center for Systems Biology

    Boston, United States

    1 h-index

    11 publications

    2.4K citations

  3. Harvard University

    Cambridge, United States

    1 h-index

    11 publications

    2.4K citations

  4. Dana-Farber Cancer Institute

    Boston, United States

    1 h-index

    1 publications

    218 citations

  5. Brigham and Women's Hospital

    Boston, United States

    1 h-index

    5 publications

    1.1K citations

  6. California Institute of Technology

    Pasadena, United States

    1 h-index

    5 publications

    110 citations

  7. Centre for Inflammation Research

    Edinburgh, United Kingdom

    1 publications

    30 citations

  8. University of Edinburgh

    Edinburgh, United Kingdom

    1 publications

    30 citations

1–8 of 6

Venues

  1. Methods in molecular biology

    Book series · 1 publications · 114 citations

    1

    h-index

  2. Development

    1 publications · 22 citations

    1

    h-index

  3. Nature Biotechnology

    1 publications · 778 citations

    1

    h-index

  4. Cancer Discovery

    1 publications · 218 citations

    1

    h-index

  5. Nature Communications

    1 publications · 30 citations

1–5