Concepedia

Hepatic Sinusoid Engineering

Hepatic Sinusoid Engineering is a tissue engineering strategy that specifically recapitulates the structural and functional microarchitecture of liver sinusoids by integrating sinusoidal endothelial cells, specialized extracellular matrix, and dynamic fluid flow to enable physiologically relevant liver cell interactions and mass transfer in engineered hepatic tissues.

24

Publications

2.8K

Citations

152

Authors

63

Institutions

Publications per year

2017–2026

9

Parents

Publications

24

Cells of the hepatic sinusoid

Toos Daemen, J Koudstaal, Gl Scherphof et al. · 1989 · 589 citations

, , +7

Cells of the hepatic sinusoid

B Portmann · Journal of Hepatology · 1998 · 561 citations

, , +7

An artificial liver sinusoid with a microfluidic endothelial‐like barrier for primary hepatocyte culture

Philip Lee, Paul J. Hung, Luke P. Lee · Biotechnology and Bioengineering · 2007 · 505 citations

, , +15

Investigating Nonalcoholic Fatty Liver Disease in a Liver-on-a-Chip Microfluidic Device

Manuele Gori, Maria Chiara Simonelli, Sara Maria Giannitelli et al. · PLoS ONE · 2016 · 172 citations · Full text

, , +17

On-Chip Construction of Liver Lobule-like Microtissue and Its Application for Adverse Drug Reaction Assay

Chao Ma, Lei Zhao, En‐Min Zhou et al. · Analytical Chemistry · 2016 · 143 citations

, , +17

1–5 of 24

Authors

152

  1. JL
    Jing Liu

    Tianjin University, China

    2 publications · 77 citations

    2

    h-index

  2. HB
    Holger Becker

    Microfluidic ChipShop (Germany), Germany

    2 publications · 106 citations

    2

    h-index

  3. KT
    Kazuo Tanishita

    Keio University, Japan

    2 publications · 58 citations

    2

    h-index

  4. HY
    Hiroshi Yagi

    Keio University, Japan

    2 publications · 89 citations

    2

    h-index

  5. MS
    Martin Stelzle

    Natural and Medical Sciences Institute, Germany

    2 publications · 106 citations

    2

    h-index

1–5 of 152

Institutions

63

  1. Microfluidic ChipShop (Germany)

    Jena, Germany

    2 h-index

    3 publications

    125 citations

  2. Drexel University

    Philadelphia, United States

    2 h-index

    6 publications

    475 citations

  3. University of Washington

    Seattle, United States

    2 h-index

    2 publications

    77 citations

  4. Natural and Medical Sciences Institute

    Reutlingen, Germany

    2 h-index

    20 publications

    924 citations

  5. Massachusetts General Hospital

    Boston, United States

    2 h-index

    5 publications

    327 citations

  6. Harvard University

    Cambridge, United States

    2 h-index

    5 publications

    327 citations

  7. University of Science and Technology of China

    Hefei, China

    2 h-index

    17 publications

    752 citations

  8. Leipzig University

    Leipzig, Germany

    2 h-index

    3 publications

    193 citations

1–8 of 63

Venues

  1. Biofabrication

    3 publications · 186 citations

    3

    h-index

  2. PLoS ONE

    2 publications · 208 citations

    2

    h-index

  3. Tissue Engineering Part A

    2 publications · 67 citations

    2

    h-index

  4. Biomedical Microdevices

    2 publications · 106 citations

    2

    h-index

  5. Methods in cell biology

    Book series · 1 publications · 19 citations

    1

    h-index

1–5