Concepedia

Heme Autoxidation

Heme Autoxidation is a chemical process in which the ferrous iron (Fe²⁺) within the heme prosthetic group of a hemoprotein undergoes spontaneous oxidation to the ferric state (Fe³⁺) without enzymatic catalysis, thereby rendering the protein incapable of normal oxygen binding and transport.

173

Publications

9.4K

Citations

662

Authors

251

Institutions

Publications per year

2017–2026

13

Parents

Publications

173

Heme oxygenase and oxidative stress. Evidence of involvement of bilirubin as physiological protector against oxidative damage

Susana Llesuy, Marı́a L. Tomaro · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · 1994 · 300 citations

, , +17

Control of the catalytic activity of prosthetic heme by the structure of hemoproteins

Paul R. Ortiz de Montellano · Accounts of Chemical Research · 1987 · 262 citations

, , +13

[4] Preparation of derivatives of ferrous and ferric hemoglobin

Ernesto E. Di Iorio · Methods in enzymology on CD-ROM/Methods in enzymology · 1981 · 246 citations

, , +10

Heme oxygenase: Protective gene or Trojan horse

Jeffrey L. Platt, Karl A. Nath · Nature Medicine · 1998 · 235 citations

, , +13

The 2.0 A structure of human ferrochelatase, the terminal enzyme of heme biosynthesis.

Chia‐Kuei Wu, Harry A. Dailey, John P. Rose et al. · Nature Structural Biology · 2001 · 227 citations

, , +14

1–5 of 173

Authors

662

  1. JM
    Joseph M. Rifkind

    National Institute on Aging, United States

    7 publications · 781 citations

    7

    h-index

  2. KS
    Keiji Shikama

    Tohoku University, Japan

    7 publications · 277 citations

    7

    h-index

  3. AM
    Ariki Matsuoka

    Tohoku University, Japan

    6 publications · 186 citations

    6

    h-index

  4. PR
    Paul R. Ortiz de Montellano

    University of California, San Francisco, United States

    5 publications · 415 citations

    5

    h-index

  5. EN
    Enika Nagababu

    National Institute on Aging, United States

    5 publications · 564 citations

    5

    h-index

1–5 of 662

Institutions

251

  1. Tohoku University

    Sendai, Japan

    7 h-index

    23 publications

    834 citations

  2. National Institute on Aging

    Baltimore, United States

    6 h-index

    18 publications

    2.1K citations

  3. Wayne State University

    Detroit, United States

    6 h-index

    27 publications

    1.7K citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    5 h-index

    14 publications

    383 citations

  5. National Institutes of Health

    Bethesda, United States

    5 h-index

    16 publications

    2K citations

  6. University of California, San Francisco

    San Francisco, United States

    5 h-index

    14 publications

    452 citations

  7. University of Rome Tor Vergata

    Rome, Italy

    4 h-index

    7 publications

    108 citations

  8. Albert Einstein College of Medicine

    Bronx, United States

    4 h-index

    11 publications

    580 citations

1–8 of 251

Venues

  1. Journal of Biological Chemistry

    JBC · 15 publications · 808 citations

    15

    h-index

  2. Journal of the American Chemical Society

    JACS · 13 publications · 761 citations

    13

    h-index

  3. Biochemistry

    15 publications · 751 citations

    13

    h-index

  4. Biochemical and Biophysical Research Communications

    BBRC · 11 publications · 532 citations

    11

    h-index

  5. JBIC Journal of Biological Inorganic Chemistry

    7 publications · 207 citations

    7

    h-index

1–5