Concepedia

Hedgehog Gradient Formation

Hedgehog Gradient Formation is a biological mechanism that establishes a concentration gradient of Hedgehog signaling molecules across developing tissues, thereby directing spatially resolved cellular responses during embryonic patterning.

19

Publications

2.2K

Citations

95

Authors

45

Institutions

Publications per year

2017–2026

5

Parents

Publications

19

Interpretation of the sonic hedgehog morphogen gradient by a temporal adaptation mechanism

Éric Dessaud, Lin Yang, Katy Hill et al. · Nature · 2007 · 642 citations · Full text

, , +14

Palmitoylation is required for the production of a soluble multimeric Hedgehog protein complex and long-range signaling in vertebrates

Miao-Hsueh Chen, Yajun Li, Takatoshi Kawakami et al. · Genes & Development · 2004 · 365 citations · Full text

, , +17

Cytonemes are required for the establishment of a normal Hedgehog morphogen gradient in Drosophila epithelia

Marcus Bischoff, Ana‐Citlali Gradilla, Irene Seijo-Barandiarán et al. · Nature Cell Biology · 2013 · 258 citations · Full text

, , +14

Dispatched mediates Hedgehog basolateral release to form the long-range morphogenetic gradient in the <i>Drosophila</i> wing disk epithelium

Ainhoa Callejo, Aphrodite Bilioni, Emanuela Mollica et al. · Proceedings of the National Academy of Sciences · 2011 · 173 citations · Full text

, , +17

A Highly Conserved Amino-terminal Region of Sonic Hedgehog Is Required for the Formation of Its Freely Diffusible Multimeric Form

John A. Goetz, Samer Singh, Liza M. Suber et al. · Journal of Biological Chemistry · 2005 · 127 citations · Full text

, , +15

1–5 of 19

Authors

95

  1. IG
    Isabel Guerrero

    Centro de Biología Molecular Severo Ochoa, Spain

    6 publications · 603 citations

    6

    h-index

  2. IS
    Irene Seijo-Barandiarán

    Universidad Autónoma de Madrid, Spain

    4 publications · 416 citations

    4

    h-index

  3. LG
    Laura González‐Méndez

    Universidad Autónoma de Madrid, Spain

    3 publications · 399 citations

    3

    h-index

  4. AA
    Adrián Aguirre‐Tamaral

    Centro de Biología Molecular Severo Ochoa, Spain

    2 publications · 37 citations

    2

    h-index

  5. GA
    Germán Andrés

    Centro de Biología Molecular Severo Ochoa, Spain

    2 publications · 431 citations

    2

    h-index

1–5 of 95

Institutions

45

  1. Universidad Autónoma de Madrid

    Madrid, Spain

    6 h-index

    32 publications

    3.9K citations

  2. Centro de Biología Molecular Severo Ochoa

    Madrid, Spain

    6 h-index

    32 publications

    3.9K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    2 h-index

    10 publications

    119 citations

  4. Cleveland Clinic Lerner College of Medicine

    Cleveland, United States

    1 h-index

    6 publications

    426 citations

  5. University of California, San Francisco

    San Francisco, United States

    1 h-index

    5 publications

    1.8K citations

  6. Dartmouth–Hitchcock Medical Center

    Lebanon, United States

    1 h-index

    1 publications

    127 citations

  7. Institut Curie

    Paris, France

    1 h-index

    2 publications

    22 citations

  8. Columbia University

    New York, United States

    1 h-index

    1 publications

    110 citations

1–8 of 45

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 2 publications · 278 citations

    2

    h-index

  2. Nature

    2 publications · 752 citations

    2

    h-index

  3. eLife

    2 publications · 141 citations

    2

    h-index

  4. PLoS Computational Biology

    1 publications · 14 citations

    1

    h-index

  5. Genes & Development

    1 publications · 365 citations

    1

    h-index

1–5