Concepedia

Hapten-mediated Hypersensitivity

Hapten-Mediated Hypersensitivity is a type of delayed hypersensitivity reaction in which small drug molecules, known as haptens, bind covalently to endogenous proteins in the renal interstitium, thereby forming immunogenic complexes that trigger a T-cell-mediated immune response leading to interstitial inflammation.

124

Publications

5.5K

Citations

399

Authors

136

Institutions

Publications per year

2017–2026

5

Parents

Publications

124

Delayed Hypersensitivity <i>in Vitro</i>

John R. David, Salah Al‐Askari, H. Sherwood Lawrence et al. · The Journal of Immunology · 1964 · 347 citations

, , +10

IMMUNOLOGICAL SPECIFICITY OF DELAYED AND IMMEDIATE HYPERSENSITIVITY REACTIONS

Baruj Benacerraf, B.B. Levine · The Journal of Experimental Medicine · 1962 · 223 citations · Full text

, , +15

α-Melanocyte-stimulating hormone induces hapten-specific tolerance in mice

Stephan Grabbe, Ranjit Bhardwaj, Karsten Mahnke et al. · The Journal of Immunology · 1996 · 152 citations · Full text

, , +17

Molecular basis of a mouse strain-specific anti-hapten response

Dennis Y. Loh, Alfred L.M. Bothwell, Mary E. White‐Scharf et al. · Cell · 1983 · 150 citations

, , +7

Role of the clotting system in cell-mediated hypersensitivity. II. Kinetics of fibrinogen/fibrin accumulation and vascular permeability changes in tuberculin and cutaneous basophil hypersensitivity reactions.

Robert B. Colvin, Harold F. Dvorak · PubMed · 1975 · 149 citations

, , +14

1–5 of 124

Authors

399

  1. SL
    Sidney Leskowitz

    Massachusetts General Hospital, United States

    9 publications · 288 citations

    9

    h-index

  2. BB
    Baruj Benacerraf

    Harvard University, United States

    5 publications · 441 citations

    5

    h-index

  3. JR
    John R. David

    Harvard University, United States

    4 publications · 544 citations

    4

    h-index

  4. HS
    H. Snippe

    Utrecht University, Netherlands

    4 publications · 46 citations

    4

    h-index

  5. CJ
    Clifford J. Bellone

    Saint Louis University, United States

    4 publications · 58 citations

    4

    h-index

1–5 of 399

Institutions

136

  1. Harvard University

    Cambridge, United States

    12 h-index

    34 publications

    1.4K citations

  2. Massachusetts General Hospital

    Boston, United States

    6 h-index

    11 publications

    519 citations

  3. New York University

    New York, United States

    6 h-index

    18 publications

    2.4K citations

  4. Albert Einstein College of Medicine

    Bronx, United States

    3 h-index

    6 publications

    482 citations

  5. Purdue University West Lafayette

    West Lafayette, United States

    3 h-index

    5 publications

    163 citations

  6. Saint Louis University

    St Louis, United States

    3 h-index

    6 publications

    96 citations

  7. Tufts University

    Medford, United States

    3 h-index

    6 publications

    414 citations

  8. University of Minnesota

    Minneapolis, United States

    3 h-index

    5 publications

    100 citations

1–8 of 136

Venues

  1. The Journal of Experimental Medicine

    20 publications · 1.3K citations

    18

    h-index

  2. The Journal of Immunology

    JI · 23 publications · 1.2K citations

    15

    h-index

  3. PubMed

    Repository · 14 publications · 677 citations

    12

    h-index

  4. Journal of Investigative Dermatology

    JID · 8 publications · 426 citations

    8

    h-index

  5. European Journal of Immunology

    EJI · 5 publications · 177 citations

    5

    h-index

1–5