Concepedia

Haplotype-based Fine-mapping

Haplotype-Based Fine-Mapping is a genetic fine-mapping approach that leverages shared haplotype structures across individuals to localize causal variants by exploiting linkage disequilibrium patterns and ancestral recombination events within population genomes.

29

Publications

1.9K

Citations

244

Authors

104

Institutions

Publications per year

2017–2026

2

Parents

Publications

29

Haplotype-based identification of a microsomal transfer protein marker associated with the human lifespan

Bard J. Geesaman, Erica K. Benson, Stephanie Brewster et al. · Proceedings of the National Academy of Sciences · 2003 · 150 citations · Full text

, , +17

Total deletion and a missense mutation of <i>ITPR1</i> in Japanese SCA15 families

Kenju Hara, Atsushi Shiga, Hiroaki Nozaki et al. · Neurology · 2008 · 143 citations

, , +17

Simultaneous Mining of Linkage and Linkage Disequilibrium to Fine Map Quantitative Trait Loci in Outbred Half-Sib Pedigrees: Revisiting the Location of a Quantitative Trait Locus With Major Effect on Milk Production on Bovine Chromosome 14

Frédéric Farnir, Bernard Grisart, Wouter Coppieters et al. · Genetics · 2002 · 139 citations · Full text

, , +17

Massively parallel quantification of the regulatory effects of noncoding genetic variation in a human cohort

Christopher M. Vockley, Cong Guo, William H. Majoros et al. · Genome Research · 2015 · 119 citations · Full text

, , +17

Fine Mapping in 94 Inbred Mouse Strains Using a High-Density Haplotype Resource

Andrew Kirby, Hyun Min Kang, Claire M. Wade et al. · Genetics · 2010 · 108 citations · Full text

, , +17

1–5 of 29

Authors

244

  1. DC
    David Clayton

    University of Cambridge, United Kingdom

    2 publications · 150 citations

    2

    h-index

  2. JC
    Jack C. M. Dekkers

    Iowa State University, United States

    2 publications · 139 citations

    2

    h-index

  3. RL
    Rohan L. Fernando

    Iowa State University, United States

    2 publications · 139 citations

    2

    h-index

  4. MF
    M. F. Rothschild

    Iowa State University, United States

    2 publications · 139 citations

    2

    h-index

  5. LG
    L. Grapes

    Iowa State University, United States

    2 publications · 139 citations

    2

    h-index

1–5 of 244

Institutions

104

  1. University of California, Los Angeles

    Los Angeles, United States

    3 h-index

    7 publications

    638 citations

  2. Imperial College London

    London, United Kingdom

    2 h-index

    4 publications

    207 citations

  3. University of Pittsburgh

    Pittsburgh, United States

    2 h-index

    2 publications

    165 citations

  4. University of Michigan

    Ann Arbor, United States

    2 h-index

    2 publications

    162 citations

  5. Centre for Human Genetics

    Oxford, United Kingdom

    2 h-index

    6 publications

    473 citations

  6. Center for Human Genetics

    Bar Harbor, United States

    2 h-index

    6 publications

    474 citations

  7. Iowa State University

    Ames, United States

    2 h-index

    8 publications

    556 citations

  8. Harvard University

    Cambridge, United States

    2 h-index

    5 publications

    330 citations

1–8 of 104

Venues

  1. Genetics

    6 publications · 482 citations

    6

    h-index

  2. Genetic Epidemiology

    3 publications · 177 citations

    3

    h-index

  3. Human Molecular Genetics

    2 publications · 64 citations

    2

    h-index

  4. Genome Research

    GR · 2 publications · 157 citations

    2

    h-index

  5. Annals of Human Genetics

    2 publications · 150 citations

    2

    h-index

1–5