Concepedia

Haplotype-based Background Selection

Haplotype-Based Background Selection is a methodological framework in population genetics that models the effects of purifying selection on linked neutral variation by explicitly incorporating haplotype structure to distinguish selected regions from background genomic variation.

4

Publications

390

Citations

32

Authors

23

Institutions

Publications per year

2017–2026

2

Parents

Publications

4

CFTR gene mutations - including three novel nucleotide substitutions - and haplotype background in patients with asthma, disseminated bronchiectasis and chronic obstructive pulmonary disease

Maria Tzetis, Alexandra Efthymiadou, Stefanos Strofalis et al. · Human Genetics · 2001 · 139 citations

, , +14

Haplotype selection as an adaptive mechanism in the protozoan pathogen Leishmania donovani

Pascale Pescher, Giovanni Bussotti, Franck Dumetz et al. · Nature Ecology & Evolution · 2017 · 130 citations

, , +12

Apolipoprotein L1 (APOL1) risk variant toxicity depends on the haplotype background

Herbert Lannon, Shrijal S. Shah, Leny Dias et al. · Kidney International · 2019 · 68 citations · Full text

, , +11

Comparisons of Site- and Haplotype-Frequency Methods for Detecting Positive Selection

Kai Zeng, Shuhei Mano, Suhua Shi et al. · Molecular Biology and Evolution · 2007 · 53 citations

, , +10

1–4 of 4

Authors

32

  1. DJ
    David J. Friedman

    Beth Israel Deaconess Medical Center, United States

    1 publications · 68 citations

    1

    h-index

  2. MT
    Maria Tzetis

    Children's Hospital Agia Sophia, Greece

    1 publications · 139 citations

    1

    h-index

  3. SS
    Suhua Shi

    Sun Yat-sen University, China

    1 publications · 53 citations

    1

    h-index

  4. GF
    Gérald F. Späth

    Institut Pasteur, France

    1 publications · 130 citations

    1

    h-index

  5. FD
    Franck Dumetz

    University of Antwerp, Belgium

    1 publications · 130 citations

    1

    h-index

1–5 of 32

Institutions

23

  1. Inserm

    Paris, France

    1 h-index

    2 publications

    260 citations

  2. Instituut voor Tropische Geneeskunde

    Antwerp, Belgium

    1 h-index

    4 publications

    520 citations

  3. Nagoya University

    Nagoya, Japan

    1 h-index

    1 publications

    53 citations

  4. Broad Institute

    Cambridge, United States

    1 h-index

    2 publications

    136 citations

  5. University of Chicago

    Chicago, United States

    1 h-index

    1 publications

    53 citations

  6. National and Kapodistrian University of Athens

    Athens, Greece

    1 h-index

    1 publications

    139 citations

  7. Sun Yat-sen University

    Guangzhou, China

    1 h-index

    2 publications

    106 citations

  8. Harvard University

    Cambridge, United States

    1 h-index

    7 publications

    476 citations

1–8 of 23

Venues

  1. Nature Ecology & Evolution

    1 publications · 130 citations

    1

    h-index

  2. Molecular Biology and Evolution

    MBE · 1 publications · 53 citations

    1

    h-index

  3. Kidney International

    1 publications · 68 citations

    1

    h-index

  4. Human Genetics

    1 publications · 139 citations

    1

    h-index

1–4