Concepedia

Halorhodopsins

Halorhodopsin is a light-sensitive ion pump of microbial origin that, upon activation by yellow light, selectively transports chloride ions into neurons to induce hyperpolarization and thereby enable optical inhibition of neuronal activity in optogenetic experiments.

374

Publications

30.5K

Citations

1K

Authors

311

Institutions

Publications per year

2017–2026

28

Variants

Halorhodopsin

Parents

Publications

374

Rhodopsin-like Protein from the Purple Membrane of Halobacterium halobium

Dieter Oesterhelt, Walther Stoeckenius · Nature New Biology · 1971 · 2.1K citations

, , +10

Functions of a New Photoreceptor Membrane

Dieter Oesterhelt, Walther Stoeckenius · Proceedings of the National Academy of Sciences · 1973 · 1.1K citations · Full text

, , +17

Bacteriorhodopsin: a light-driven proton pump in Halobacterium Halobium

Richard H. Lozier, Roberto A. Bogomolni, Walther Stoeckenius · Biophysical Journal · 1975 · 1K citations · Full text

, , +13

All-optical electrophysiology in mammalian neurons using engineered microbial rhodopsins

Daniel R. Hochbaum, Yongxin Zhao, Samouil L. Farhi et al. · Nature Methods · 2014 · 825 citations · Full text

, , +16

Genetic Reactivation of Cone Photoreceptors Restores Visual Responses in Retinitis Pigmentosa

Volker Busskamp, Jens Duebel, D. Bálya et al. · Science · 2010 · 643 citations · Full text

, , +16

1–5 of 374

Authors

1K

  1. DO
    Dieter Oesterhelt

    Max Planck Institute of Biochemistry, Germany

    56 publications · 7.6K citations

    42

    h-index

  2. JΚ
    Janos Κ. Lanyi

    University of California, Irvine, United States

    36 publications · 2.5K citations

    25

    h-index

  3. JL
    John L. Spudich

    The University of Texas Health Science Center at Houston, United States

    19 publications · 1.3K citations

    17

    h-index

  4. NK
    Naoki Kamo

    Hokkaido University, Japan

    25 publications · 1K citations

    17

    h-index

  5. MD
    Makoto Demura

    Hokkaido University, Japan

    18 publications · 504 citations

    15

    h-index

1–5 of 1K

Institutions

311

  1. Max Planck Institute of Biochemistry

    Martinsried, Germany

    34 h-index

    98 publications

    8.1K citations

  2. Max Planck Society

    Munich, Germany

    22 h-index

    57 publications

    3.3K citations

  3. University of California, Irvine

    Irvine, United States

    21 h-index

    71 publications

    4K citations

  4. Hokkaido University

    Sapporo, Japan

    20 h-index

    142 publications

    5K citations

  5. University of California, San Francisco

    San Francisco, United States

    15 h-index

    46 publications

    11K citations

  6. The University of Tokyo

    Tokyo, Japan

    13 h-index

    44 publications

    2K citations

  7. The University of Osaka

    Osaka, Japan

    13 h-index

    36 publications

    2.2K citations

  8. Massachusetts Institute of Technology

    Cambridge, United States

    13 h-index

    47 publications

    12.7K citations

1–8 of 311

Venues

  1. Biochemistry

    40 publications · 2K citations

    29

    h-index

  2. Biophysical Journal

    36 publications · 2.9K citations

    24

    h-index

  3. Journal of Biological Chemistry

    JBC · 26 publications · 1.9K citations

    22

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 22 publications · 3.7K citations

    22

    h-index

  5. Photochemistry and Photobiology

    23 publications · 804 citations

    18

    h-index

1–5