Concepedia

Half-life Differences

Half-Life Differences is a toxicokinetic parameter that refers to the variation in the time required for the concentration of a xenobiotic to reduce by half in different species due to interspecies differences in metabolic rate, distribution, and clearance mechanisms.

303

Publications

18.2K

Citations

1.4K

Authors

444

Institutions

Publications per year

2017–2026

30

Parents

Publications

303

Half-lives of PFOS, PFHxS and PFOA after end of exposure to contaminated drinking water

Ying Li, Tony Fletcher, Dániel Mucs et al. · Occupational and Environmental Medicine · 2017 · 798 citations · Full text

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Degradation rates of oral resorbable implants (polylactates and polyglycolates): Rate modification with changes in PLA/PGA copolymer ratios

Robert A. Miller, John M. Brady, Duane E. Cutright · Journal of Biomedical Materials Research · 1977 · 714 citations

, , +14

Biological Activity of Recombinant Human Interleukin-2 Produced in <i>Escherichia coli</i>

Steven A. Rosenberg, Elizabeth A. Grimm, Michael McGrogan et al. · Science · 1984 · 599 citations

, , +15

Circulating versus local renin-angiotensin system in cardiovascular homeostasis.

Victor J. Dzau · PubMed · 1988 · 476 citations

, , +14

The half-lives of serum immunoglobulins in adult mice

Paulo Vieira, Klaus Rajewsky · European Journal of Immunology · 1988 · 460 citations

, , +13

1–5 of 303

Authors

1.4K

  1. IS
    Inger Sandlie

    University of Oslo, Norway

    3 publications · 158 citations

    3

    h-index

  2. JT
    Jan Terje Andersen

    University of Oslo, Norway

    3 publications · 158 citations

    3

    h-index

  3. TB
    Tom Bergan

    University of Oslo, Norway

    3 publications · 132 citations

    3

    h-index

  4. ES
    E. Sally Ward

    The University of Texas Southwestern Medical Center, United States

    2 publications · 268 citations

    2

    h-index

  5. SF
    Stian Foss

    University of Oslo, Norway

    2 publications · 85 citations

    2

    h-index

1–5 of 1.4K

Institutions

444

  1. University of Oslo

    Oslo, Norway

    5 h-index

    28 publications

    1.7K citations

  2. Massachusetts General Hospital

    Boston, United States

    5 h-index

    9 publications

    576 citations

  3. University of Oxford

    Oxford, United Kingdom

    5 h-index

    39 publications

    2K citations

  4. Harvard University

    Cambridge, United States

    4 h-index

    6 publications

    400 citations

  5. Novartis (Switzerland)

    Basel, Switzerland

    4 h-index

    13 publications

    3.3K citations

  6. Karolinska University Hospital

    Stockholm, Sweden

    4 h-index

    9 publications

    615 citations

  7. University of Michigan

    Ann Arbor, United States

    4 h-index

    29 publications

    2.4K citations

  8. Centers for Disease Control and Prevention

    Atlanta, United States

    4 h-index

    9 publications

    796 citations

1–8 of 444

Venues

  1. PubMed

    Repository · 34 publications · 1.6K citations

    20

    h-index

  2. Antimicrobial Agents and Chemotherapy

    AAC · 17 publications · 884 citations

    17

    h-index

  3. Journal of Clinical Investigation

    JCI · 8 publications · 1.1K citations

    8

    h-index

  4. The Journal of Clinical Endocrinology & Metabolism

    JCEM · 8 publications · 454 citations

    8

    h-index

  5. Clinical Pharmacology & Therapeutics

    CPT · 7 publications · 545 citations

    7

    h-index

1–5