Concepedia

Gonadal Axis Aging

Gonadal Axis Aging is a biological framework describing the progressive dysregulation of the hypothalamic-pituitary-gonadal axis characterized by declining sex steroid production and impaired feedback sensitivity, distinguishing it from other neuroendocrine aging processes through its specific impact on reproductive endocrinology and related physiological functions.

143

Publications

9.2K

Citations

530

Authors

264

Institutions

Publications per year

2017–2026

16

Variants

Hpg Axis AgingHypothalamic-pituitary-gonadal Axis Aging

Parents

Publications

143

Testosterone Replacement in Older Hypogonadal Men: A 12-Month Randomized Controlled Trial

Rahmawati Sih, John E. Morley, Fran E. Kaiser et al. · The Journal of Clinical Endocrinology & Metabolism · 1997 · 895 citations · Full text

, , +17

Loss of Circadian Rhythmicity in Blood Testosterone Levels with Aging in Normal Men*

William J. Bremner, Michael V. Vitiello, Patricia N. Prinz · The Journal of Clinical Endocrinology & Metabolism · 1983 · 795 citations

, , +17

Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α‐glucosidase inhibitor or a Nrf2‐inducer

Randy Strong, Richard A. Miller, Adam Antebi et al. · Aging Cell · 2016 · 377 citations · Full text

, , +17

Older males secrete luteinizing hormone and testosterone more irregularly, and jointly more asynchronously, than younger males

Steven M. Pincus, Thomas Mulligan, Ali Iranmanesh et al. · Proceedings of the National Academy of Sciences · 1996 · 342 citations · Full text

, , +17

Neuroprotective Effects of Female Gonadal Steroids in Reproductively Senescent Female Rats

Nabil J. Alkayed, Stephanie J. Murphy, Richard J. Traystman et al. · Stroke · 2000 · 335 citations · Full text

, , +17

1–5 of 143

Authors

530

  1. JD
    Johannes D. Veldhuis

    University of Virginia, United States

    13 publications · 534 citations

    13

    h-index

  2. AI
    Ali Iranmanesh

    Salem VA Medical Center, United States

    10 publications · 805 citations

    10

    h-index

  3. DM
    Daniel M. Keenan

    University of Virginia, United States

    5 publications · 194 citations

    5

    h-index

  4. TM
    Thomas Mulligan

    Hunter Holmes McGuire VA Medical Center, United States

    5 publications · 608 citations

    5

    h-index

  5. PY
    Paul Y. Takahashi

    Mayo Clinic, United States

    4 publications · 203 citations

    4

    h-index

1–5 of 530

Institutions

264

  1. University of Virginia

    Charlottesville, United States

    10 h-index

    17 publications

    2.3K citations

  2. Mayo Clinic

    Rochester, United States

    7 h-index

    10 publications

    417 citations

  3. Geriatric Research Education and Clinical Center

    Pittsburgh, United States

    7 h-index

    16 publications

    7.2K citations

  4. Salem VA Medical Center

    Salem, United States

    6 h-index

    7 publications

    398 citations

  5. University of Michigan

    Ann Arbor, United States

    6 h-index

    18 publications

    1.3K citations

  6. The University of Texas Health Science Center at Houston

    Houston, United States

    4 h-index

    16 publications

    909 citations

  7. The University of Texas at San Antonio Health Science Center

    San Antonio, United States

    4 h-index

    11 publications

    2.4K citations

  8. Johns Hopkins University

    Baltimore, United States

    4 h-index

    15 publications

    1.6K citations

1–8 of 264

Venues

  1. Endocrinology

    21 publications · 1.1K citations

    17

    h-index

  2. The Journal of Clinical Endocrinology & Metabolism

    JCEM · 13 publications · 2.4K citations

    13

    h-index

  3. Biology of Reproduction

    11 publications · 524 citations

    11

    h-index

  4. Journal of Neuroendocrinology

    5 publications · 74 citations

    5

    h-index

  5. Clinical Endocrinology

    5 publications · 396 citations

    5

    h-index

1–5