Concepedia

Glycosynthase Technology

Glycosynthase Technology is a protein engineering methodology that employs mutated glycosidases incapable of hydrolysis but capable of synthesizing glycosidic bonds through transglycosylation, enabling efficient and stereoselective oligosaccharide assembly.

72

Publications

3.5K

Citations

283

Authors

102

Institutions

Publications per year

2017–2026

11

Parents

Publications

72

Glycosynthases:  Mutant Glycosidases for Oligosaccharide Synthesis

Lloyd Mackenzie, Qingping Wang, R. Antony J. Warren et al. · Journal of the American Chemical Society · 1998 · 535 citations

, , +15

Glycosynthases Enable a Highly Efficient Chemoenzymatic Synthesis of <i>N</i>-Glycoproteins Carrying Intact Natural <i>N</i>-Glycans

Wei Huang, Cishan Li, Bing Li et al. · Journal of the American Chemical Society · 2009 · 181 citations

, , +17

A High‐Yielding Biocatalytic Process for the Production of 2‐<i>O</i>‐(α‐<scp>D</scp>‐glucopyranosyl)‐<i>sn</i>‐glycerol, a Natural Osmolyte and Useful Moisturizing Ingredient

Christiane Goedl, Thornthan Sawangwan, Mario Mueller et al. · Angewandte Chemie International Edition · 2008 · 127 citations

, , +17

Directed Evolution of a Glycosynthase from Agrobacterium sp. Increases Its Catalytic Activity Dramatically and Expands Its Substrate Repertoire

Young‐Wan Kim, Seung Seo Lee, R. Antony J. Warren et al. · Journal of Biological Chemistry · 2004 · 125 citations · Full text

, , +17

1,2‐α‐<scp>l</scp>‐Fucosynthase: A glycosynthase derived from an inverting α‐glycosidase with an unusual reaction mechanism

Jun Wada, Yuji Honda, Masamichi Nagae et al. · FEBS Letters · 2008 · 106 citations

, , +17

1–5 of 72

Authors

283

  1. SG
    Stephen G. Withers

    University of British Columbia, Canada

    15 publications · 1.3K citations

    15

    h-index

  2. MM
    Marco Moracci

    Institute of Protein Biochemistry, Italy

    9 publications · 412 citations

    9

    h-index

  3. MR
    Mosé Rossi

    Institute of Protein Biochemistry, Italy

    8 publications · 339 citations

    8

    h-index

  4. RA
    R. Antony J. Warren

    University of British Columbia, Canada

    7 publications · 1K citations

    7

    h-index

  5. LW
    Lai‐Xi Wang

    University of Maryland, Baltimore, United States

    6 publications · 488 citations

    6

    h-index

1–5 of 283

Institutions

102

  1. University of British Columbia

    Vancouver, Canada

    14 h-index

    57 publications

    5.5K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    8 h-index

    35 publications

    923 citations

  3. Institute of Protein Biochemistry

    Naples, Italy

    8 h-index

    29 publications

    1.4K citations

  4. National Research Council

    Rome, Italy

    6 h-index

    27 publications

    1.2K citations

  5. Kyoto University

    Kyoto, Japan

    5 h-index

    18 publications

    2K citations

  6. University of Naples Federico II

    Naples, Italy

    5 h-index

    11 publications

    385 citations

  7. Graz University of Technology

    Graz, Austria

    5 h-index

    15 publications

    949 citations

  8. University of York

    York, United Kingdom

    4 h-index

    9 publications

    359 citations

1–8 of 102

Venues

  1. Journal of the American Chemical Society

    JACS · 4 publications · 861 citations

    4

    h-index

  2. Angewandte Chemie International Edition

    4 publications · 265 citations

    4

    h-index

  3. Chemistry & Biology

    3 publications · 220 citations

    3

    h-index

  4. Biomacromolecules

    3 publications · 79 citations

    3

    h-index

  5. Glycobiology

    3 publications · 97 citations

    3

    h-index

1–5