Concepedia

Glutamine Cycle

The "Glutamine Cycle" is a metabolic pathway in the central nervous system that shuttles nitrogen and carbon between neurons and astrocytes, wherein glutamine synthesized in astrocytes from glutamate is released and taken up by neurons to replenish the neurotransmitter glutamate pool.

161

Publications

11.4K

Citations

741

Authors

294

Institutions

Publications per year

2017–2026

26

Variants

Glutamate-glutamine Cycle

Parents

Publications

161

Glucose-Independent Glutamine Metabolism via TCA Cycling for Proliferation and Survival in B Cells

Anne Le, Andrew N. Lane, Max Hamaker et al. · Cell Metabolism · 2012 · 1.1K citations · Full text

, , +13

SUBCELLULAR DISTRIBUTION OF THE ENZYMES OF THE GLUTAMIC ACID, GLUTAMINE AND γ‐AMINOBUTYRIC ACID CYCLES IN RAT BRAIN*

Leon Salganicoff, E. De Robertis · Journal of Neurochemistry · 1965 · 543 citations

, , +16

Determination of the rate of the glutamate/glutamine cycle in the human brain by <i>in vivo</i> <sup>13</sup> C NMR

Jun Shen, Kitt Falk Petersen, Kevin L. Behar et al. · Proceedings of the National Academy of Sciences · 1999 · 461 citations · Full text

, , +17

The contribution of GABA to glutamate/glutamine cycling and energy metabolism in the rat cortex <i>in vivo</i>

Anant B. Patel, Robin A. de Graaf, Graeme F. Mason et al. · Proceedings of the National Academy of Sciences · 2005 · 343 citations

, , +17

<i>In vivo</i> <sup>13</sup> C NMR measurements of cerebral glutamine synthesis as evidence for glutamate–glutamine cycling

Nicola R. Sibson, Amit Dhankhar, Graeme F. Mason et al. · Proceedings of the National Academy of Sciences · 1997 · 318 citations · Full text

, , +17

1–5 of 161

Authors

741

  1. DL
    Douglas L. Rothman

    Yale University, United States

    13 publications · 2K citations

    13

    h-index

  2. KL
    Kevin L. Behar

    Yale University, United States

    9 publications · 1.6K citations

    9

    h-index

  3. RA
    Robin A. de Graaf

    Yale University, United States

    6 publications · 770 citations

    6

    h-index

  4. GF
    Graeme F. Mason

    Yale University, United States

    5 publications · 1.4K citations

    5

    h-index

  5. DH
    Dieter Häussinger

    Heinrich Heine University Düsseldorf, Germany

    5 publications · 558 citations

    5

    h-index

1–5 of 741

Institutions

294

  1. Yale University

    New Haven, United States

    13 h-index

    61 publications

    12.5K citations

  2. Resonance Research (United States)

    Billerica, United States

    7 h-index

    31 publications

    3.3K citations

  3. Universidad Nacional Autónoma de México

    Mexico City, Mexico

    6 h-index

    12 publications

    233 citations

  4. University Medical Center Freiburg

    Freiburg im Breisgau, Germany

    6 h-index

    8 publications

    1K citations

  5. Centre National de la Recherche Scientifique

    Paris, France

    6 h-index

    29 publications

    1.5K citations

  6. Inserm

    Paris, France

    4 h-index

    17 publications

    875 citations

  7. University of Geneva

    Geneva, Switzerland

    4 h-index

    4 publications

    205 citations

  8. University of Cambridge

    Cambridge, United Kingdom

    4 h-index

    4 publications

    240 citations

1–8 of 294

Venues

  1. Journal of Neurochemistry

    JNC · 16 publications · 1.5K citations

    15

    h-index

  2. Journal of Neuroscience Research

    JNR · 9 publications · 215 citations

    9

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 7 publications · 1.4K citations

    7

    h-index

  4. Journal of Cerebral Blood Flow & Metabolism

    6 publications · 514 citations

    6

    h-index

  5. Glia

    6 publications · 325 citations

    6

    h-index

1–5