Concepedia

Genotype-specific Dose Optimization

Genotype-Specific Dose Optimization is a mutagen dose optimization strategy that tailors mutagen exposure levels to the genetic makeup of a specific genotype, distinguishing it from generalized dose approaches by prioritizing genotype-dependent sensitivity and response variability in mutation induction.

6

Publications

423

Citations

56

Authors

31

Institutions

Publications per year

2017–2026

3

Parents

Publications

6

Successful Efavirenz Dose Reduction in HIV Type 1-Infected Individuals with Cytochrome P450 2B6 *6 and *26

Hiroyuki Gatanaga, Tsunefusa Hayashida, K. Tsuchiya et al. · Clinical Infectious Diseases · 2007 · 222 citations

, , +17

Optimizing Dietary Restriction for Genetic Epistasis Analysis and Gene Discovery in C. elegans

William B. Mair, Siler H. Panowski, Reuben J. Shaw et al. · PLoS ONE · 2009 · 85 citations · Full text

, , +13

The impact of genetic polymorphisms on the pharmacokinetics of efavirenz in African children

Andrzej Bienczak, Adrian Cook, Lubbe Wiesner et al. · British Journal of Clinical Pharmacology · 2016 · 37 citations · Full text

, , +17

More Dose-dependent Side Effects with Mercaptopurine over Azathioprine in IBD Treatment Due to Relatively Higher Dosing

Mark M. T. J. Broekman, Marieke J. H. Coenen, Corine J. van Marrewijk et al. · Inflammatory Bowel Diseases · 2017 · 33 citations · Full text

, , +15

Optimising the dosage of ethyl methanesulphonate mutagenesis in selected wheat genotypes

Boluwatife M. OlaOlorun, Hussein Shimelis, Isack Mathew et al. · South African Journal of Plant and Soil · 2019 · 25 citations

, , +13

1–5 of 6

Authors

56

  1. AO
    Adeniyi Olagunju

    University of Liverpool, United Kingdom

    1 publications · 37 citations

    1

    h-index

  2. BM
    Boluwatife M. OlaOlorun

    University of KwaZulu-Natal, South Africa

    1 publications · 25 citations

    1

    h-index

  3. KF
    Katsuya Fujimoto

    Hokkaido University, Japan

    1 publications · 222 citations

    1

    h-index

  4. TS
    T Shirasaka

    National Cancer Institute, United States

    1 publications · 222 citations

    1

    h-index

  5. MU
    Mikio Ueda

    Kanazawa University, Japan

    1 publications · 222 citations

    1

    h-index

1–5 of 56

Institutions

31

  1. Radboud University Medical Center

    Nijmegen, The Netherlands

    2 h-index

    6 publications

    202 citations

  2. Radboud University Nijmegen

    Nijmegen, The Netherlands

    2 h-index

    7 publications

    235 citations

  3. Ishikawa Prefectural Central Hospital

    Kanazawa, Japan

    1 h-index

    1 publications

    222 citations

  4. National Kyushu Medical Center

    Fukuoka, Japan

    1 h-index

    1 publications

    222 citations

  5. University Teaching Hospital

    Lusaka, Zambia

    1 h-index

    1 publications

    37 citations

  6. Saitama International Medical Center

    Saitama, Japan

    1 h-index

    5 publications

    1.1K citations

  7. Máxima Medisch Centrum

    Veldhoven, The Netherlands

    1 h-index

    1 publications

    33 citations

  8. National Hospital Organization Saitama Hospital

    Saitama, Japan

    1 h-index

    1 publications

    222 citations

1–8 of 31

Venues

  1. South African Journal of Plant and Soil

    1 publications · 25 citations

    1

    h-index

  2. PLoS ONE

    1 publications · 85 citations

    1

    h-index

  3. Inflammatory Bowel Diseases

    1 publications · 33 citations

    1

    h-index

  4. Trends in Biosciences/Trends in biosciences

    1 publications · 21 citations

    1

    h-index

  5. British Journal of Clinical Pharmacology

    BJCP · 1 publications · 37 citations

    1

    h-index

1–5