Concepedia

Genotype-guided Anticoagulation

Genotype-Guided Anticoagulation is a pharmacogenomic strategy that integrates individual genetic variation, particularly in genes such as CYP2C9 and VKORC1, to optimize the dosing and selection of anticoagulant therapy, thereby improving therapeutic efficacy and minimizing adverse drug reactions.

122

Publications

9.5K

Citations

781

Authors

286

Institutions

Publications per year

2017–2026

28

Parents

Publications

122

A Randomized Trial of Genotype-Guided Dosing of Warfarin

Munir Pirmohamed, Girvan Burnside, Niclas Eriksson et al. · New England Journal of Medicine · 2013 · 808 citations · Full text

, , +14

Randomized Trial of Genotype-Guided Versus Standard Warfarin Dosing in Patients Initiating Oral Anticoagulation

Jeffrey L. Anderson, Benjamin D. Horne, Scott M. Stevens et al. · Circulation · 2007 · 730 citations · Full text

, , +16

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for Pharmacogenetics‐Guided Warfarin Dosing: 2017 Update

JA Johnson, KE Caudle, Li Gong et al. · Clinical Pharmacology & Therapeutics · 2017 · 693 citations · Full text

, , +15

CYP4F2 genetic variant alters required warfarin dose

Michael D. Caldwell, Tarif Awad, Julie A. Johnson et al. · Blood · 2008 · 522 citations · Full text

, , +11

Common VKORC1 and GGCX polymorphisms associated with warfarin dose

Mia Wadelius, L Y Chen, Kate Downes et al. · The Pharmacogenomics Journal · 2005 · 467 citations

, , +13

1–5 of 122

Authors

781

  1. BF
    Brian F. Gage

    Washington University in St. Louis, United States

    9 publications · 2K citations

    9

    h-index

  2. MW
    Mia Wadelius

    Uppsala University, Sweden

    6 publications · 2.6K citations

    6

    h-index

  3. MP
    Munir Pirmohamed

    University of Liverpool, United Kingdom

    5 publications · 2K citations

    5

    h-index

  4. JH
    Joyce H. S. You

    Chinese University of Hong Kong, Hong Kong SAR China

    5 publications · 245 citations

    5

    h-index

  5. MW
    Mark W. Linder

    University of Louisville, United States

    4 publications · 474 citations

    4

    h-index

1–5 of 781

Institutions

286

  1. Washington University in St. Louis

    St Louis, United States

    9 h-index

    39 publications

    8.7K citations

  2. University of Florida

    Gainesville, United States

    6 h-index

    11 publications

    2.4K citations

  3. Uppsala University

    Uppsala, Sweden

    6 h-index

    14 publications

    5.6K citations

  4. University of Liverpool

    Liverpool, United Kingdom

    5 h-index

    19 publications

    6.8K citations

  5. University of Utah

    Salt Lake City, United States

    5 h-index

    16 publications

    2.4K citations

  6. Chinese University of Hong Kong

    Hong Kong, Hong Kong

    5 h-index

    12 publications

    722 citations

  7. Marshfield Clinic

    Marshfield, United States

    4 h-index

    23 publications

    6.2K citations

  8. University of Pennsylvania

    Philadelphia, United States

    4 h-index

    11 publications

    1.7K citations

1–8 of 286

Venues

  1. Clinical Pharmacology & Therapeutics

    CPT · 10 publications · 1.8K citations

    10

    h-index

  2. Thrombosis and Haemostasis

    7 publications · 377 citations

    7

    h-index

  3. Pharmacogenetics and Genomics

    6 publications · 322 citations

    6

    h-index

  4. European Journal of Clinical Pharmacology

    6 publications · 348 citations

    6

    h-index

  5. PubMed

    Repository · 6 publications · 86 citations

    6

    h-index

1–5