Kate Downes

Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression

Urmo Võsa, Annique Claringbould, Harm-Jan Westra et al. · Nature Genetics · 2021 · 2K citations · Full text

Genome-wide Association Study, Genetic Analysis, Medicine +13

Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity

Sadia Saeed, Jessica Quintin, Hindrik H. D. Kerstens et al. · Science · 2014 · 1.6K citations · Full text

Trained Immunity, Adaptive Immune System, Innate Immune System +18

The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease

William J. Astle, Heather Elding, Tao Jiang et al. · Cell · 2016 · 1.4K citations · Full text

Lineage-Specific Genome Architecture Links Enhancers and Non-coding Disease Variants to Target Gene Promoters

Biola M. Javierre, Oliver S. Burren, Steven P. Wilder et al. · Cell · 2016 · 1.1K citations · Full text

Shared and Distinct Genetic Variants in Type 1 Diabetes and Celiac Disease

Deborah J. Smyth, Vincent Plagnol, Neil Walker et al. · New England Journal of Medicine · 2008 · 751 citations · Full text