Concepedia

Genome Minimization

Genome Minimization is a computational and experimental methodology in synthetic biology that systematically identifies and eliminates non-essential genetic elements from an organism's genome to construct a minimal genome capable of supporting life under defined conditions.

27

Publications

3.7K

Citations

178

Authors

70

Institutions

Publications per year

2017–2026

13

Parents

Publications

27

Design and synthesis of a minimal bacterial genome

Clyde A. Hutchison, Ray-Yuan Chuang, Vladimir N. Noskov et al. · Science · 2016 · 1.5K citations

, , +16

Diverse uncultivated ultra-small bacterial cells in groundwater

Birgit Luef, Kyle R. Frischkorn, Kelly Wrighton et al. · Nature Communications · 2015 · 462 citations · Full text

, , +16

A minimal gene set for cellular life derived by comparison of complete bacterial genomes

Mushegian · Proc Natl Acad Sci USA · 1996 · 295 citations

, , +14

Engineering a Reduced <i>Escherichia coli</i> Genome

Vitaliy Kolisnychenko, Guy Plunkett, Christopher D. Herring et al. · Genome Research · 2002 · 288 citations · Full text

, , +17

Large-scale reduction of the <i>Bacillus subtilis</i> genome: consequences for the transcriptional network, resource allocation, and metabolism

Daniel R. Reuß, Josef Altenbuchner, Ulrike Mäder et al. · Genome Research · 2016 · 167 citations · Full text

, , +17

1–5 of 27

Authors

178

  1. KS
    Kim S. Wise

    University of Missouri, United States

    3 publications · 1.7K citations

    3

    h-index

  2. JI
    John I. Glass

    J. Craig Venter Institute, United States

    3 publications · 1.7K citations

    3

    h-index

  3. MD
    Michael D. Koob

    University of Minnesota, United States

    2 publications · 165 citations

    2

    h-index

  4. LS
    Lijie Sun

    J. Craig Venter Institute, United States

    2 publications · 1.6K citations

    2

    h-index

  5. RA
    R. Alexander Richter

    J. Craig Venter Institute, United States

    1 publications · 1.5K citations

    1

    h-index

1–5 of 178

Institutions

70

  1. J. Craig Venter Institute

    La Jolla, United States

    3 h-index

    22 publications

    23.7K citations

  2. University of Wisconsin–Madison

    Madison, United States

    2 h-index

    10 publications

    2.1K citations

  3. University of Manchester

    Manchester, United Kingdom

    1 h-index

    3 publications

    123 citations

  4. National Institute of Standards and Technology

    Gaithersburg, United States

    1 h-index

    2 publications

    3.1K citations

  5. Maastricht University

    Maastricht, The Netherlands

    1 h-index

    1 publications

    22 citations

  6. University of Stuttgart

    Stuttgart, Germany

    1 h-index

    1 publications

    167 citations

  7. Huazhong Agricultural University

    Wuhan, China

    1 h-index

    20 publications

    880 citations

  8. Indiana University Bloomington

    Bloomington, United States

    1 h-index

    3 publications

    318 citations

1–8 of 70

Venues

  1. Nature Communications

    3 publications · 570 citations

    3

    h-index

  2. Genome Research

    GR · 2 publications · 455 citations

    2

    h-index

  3. Nature

    2 publications · 120 citations

    2

    h-index

  4. Biology Direct

    BD · 1 publications · 29 citations

    1

    h-index

  5. Science

    1 publications · 1.5K citations

    1

    h-index

1–5