Concepedia

Gene Misregulation

Gene Misregulation is a biological phenomenon characterized by the aberrant expression of genes, resulting from disruptions in normal regulatory mechanisms, particularly due to altered chromatin architecture such as compromised Topologically Associating Domain boundaries.

86

Publications

4.9K

Citations

484

Authors

228

Institutions

Publications per year

2017–2026

40

Parents

Publications

86

Correlated alterations in genome organization, histone methylation, and DNA–lamin A/C interactions in Hutchinson-Gilford progeria syndrome

Rachel Patton McCord, Ashley Nazario-Toole, Haoyue Zhang et al. · Genome Research · 2012 · 325 citations · Full text

, , +17

Delta-Notch signalling and the patterning of sensory cell differentiation in the zebrafish ear: evidence from the <i>mind bomb</i> mutant

Catherine Haddon, Yun‐Jin Jiang, Lucy Smithers et al. · Development · 1998 · 288 citations

, , +15

Aberrant chromatin at genes encoding stem cell regulators in human mixed-lineage leukemia

Matthew G. Guenther, Lee N. Lawton, Tatiana Rozovskaia et al. · Genes & Development · 2008 · 277 citations · Full text

, , +17

Genome-Wide Gene Expression Analysis Reveals a Critical Role for CRYPTOCHROME1 in the Response of Arabidopsis to High Irradiance

Tatjana Kleine, Peter Kindgren, Catherine Benedict et al. · PLANT PHYSIOLOGY · 2007 · 257 citations · Full text

, , +16

Transcriptome analysis of human autosomal trisomy

David Fitzpatrick · Human Molecular Genetics · 2002 · 204 citations

, , +17

1–5 of 86

Authors

484

  1. JD
    Job Dekker

    University of Massachusetts Chan Medical School, United States

    2 publications · 518 citations

    2

    h-index

  2. XL
    Xiaozhi Li

    China Medical University, China

    2 publications · 73 citations

    2

    h-index

  3. YM
    Yutong Meng

    China Medical University, China

    2 publications · 73 citations

    2

    h-index

  4. AP
    Artūras Petronis

    Centre for Addiction and Mental Health, Canada

    2 publications · 166 citations

    2

    h-index

  5. LT
    Làszlò Tora

    Centre National de la Recherche Scientifique, France

    2 publications · 114 citations

    2

    h-index

1–5 of 484

Institutions

228

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    5 h-index

    11 publications

    1K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    4 h-index

    22 publications

    946 citations

  3. University of Pittsburgh

    Pittsburgh, United States

    3 h-index

    4 publications

    268 citations

  4. National Institutes of Health

    Bethesda, United States

    3 h-index

    7 publications

    1.1K citations

  5. Harvard University

    Cambridge, United States

    3 h-index

    6 publications

    284 citations

  6. University of Pennsylvania

    Philadelphia, United States

    3 h-index

    19 publications

    1.3K citations

  7. China Medical University

    Shenyang, China

    3 h-index

    7 publications

    206 citations

  8. University College London

    London, United Kingdom

    2 h-index

    5 publications

    607 citations

1–8 of 228

Venues

  1. Human Molecular Genetics

    5 publications · 459 citations

    5

    h-index

  2. Nature Communications

    4 publications · 120 citations

    4

    h-index

  3. Scientific Reports

    4 publications · 73 citations

    4

    h-index

  4. PLoS Genetics

    3 publications · 60 citations

    3

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 3 publications · 159 citations

    3

    h-index

1–5