Concepedia

Gene Expression Rewiring

Gene Expression Rewiring is a molecular evolutionary mechanism whereby existing genes are redeployed into new regulatory networks or functional contexts, distinguished from other gene regulatory changes by its emphasis on the large-scale reorganization of transcriptional circuits without the emergence of novel genes.

15

Publications

598

Citations

81

Authors

48

Institutions

Publications per year

2017–2026

8

Variants

Regulatory RewiringTranscriptional Rewiring

Parents

Publications

15

Evolution of Eukaryotic Transcription Circuits

Brian B. Tuch, Hao Li, Alexander D. Johnson · Science · 2008 · 158 citations

, , +15

Transcriptional rewiring over evolutionary timescales changes quantitative and qualitative properties of gene expression

Chiraj K. Dalal, Ignacio A. Zuleta, Kaitlin F. Mitchell et al. · eLife · 2016 · 69 citations · Full text

, , +17

Gene regulatory network plasticity predates a switch in function of a conserved transcription regulator

Isabel Nocedal, Eugenio Mancera, Alexander D. Johnson · eLife · 2017 · 63 citations · Full text

, , +16

Evolutionary Rewiring of Human Regulatory Networks by Waves of Genome Expansion

Davide Marnetto, Federica Mantica, Ivan Molineris et al. · The American Journal of Human Genetics · 2018 · 45 citations · Full text

, , +16

Evolutionary potential of transcription factors for gene regulatory rewiring

Claudia Igler, Mato Lagator, Gašper Tkačik et al. · Nature Ecology & Evolution · 2018 · 43 citations

, , +16

1–5 of 15

Authors

81

  1. AD
    Alexander D. Johnson

    University of California, San Francisco, United States

    3 publications · 290 citations

    3

    h-index

  2. ST
    Saburo Tsuru

    The University of Osaka, Japan

    2 publications · 43 citations

    2

    h-index

  3. MS
    Mingzhou Song

    New Mexico State University, United States

    1 publications · 19 citations

    1

    h-index

  4. FM
    Francesco M. Mancuso

    Vall d'Hebron Institute of Oncology, Spain

    1 publications · 28 citations

    1

    h-index

  5. SH
    Sridhar Hannenhalli

    University of Pennsylvania, United States

    1 publications · 13 citations

    1

    h-index

1–5 of 81

Institutions

48

  1. University of California, San Francisco

    San Francisco, United States

    3 h-index

    10 publications

    939 citations

  2. The University of Osaka

    Osaka, Japan

    2 h-index

    4 publications

    73 citations

  3. Vall d'Hebron Institut de Recerca

    Barcelona, Spain

    1 h-index

    1 publications

    28 citations

  4. Shandong University

    Jinan, China

    1 h-index

    2 publications

    40 citations

  5. Institute of Science and Technology Austria

    Klosterneuburg, Austria

    1 h-index

    5 publications

    215 citations

  6. George Washington University

    Washington, United States

    1 h-index

    1 publications

    28 citations

  7. QB3

    San Francisco, United States

    1 h-index

    2 publications

    138 citations

  8. University of Wisconsin–Madison

    Madison, United States

    1 h-index

    2 publications

    138 citations

1–8 of 48

Venues

  1. eLife

    3 publications · 146 citations

    3

    h-index

  2. Nucleic Acids Research

    2 publications · 34 citations

    2

    h-index

  3. The American Journal of Human Genetics

    AJHG · 1 publications · 45 citations

    1

    h-index

  4. Molecular Ecology

    1 publications · 26 citations

    1

    h-index

  5. PLoS neglected tropical diseases

    1 publications · 28 citations

    1

    h-index

1–5