Concepedia

Gapped Alignment Modeling

Gapped Alignment Modeling is a computational framework within Profile Hidden Markov Models that specifically accounts for insertions and deletions in biological sequence alignments by structurally embedding gap states into the model topology to distinguish homologous from non-homologous regions.

21

Publications

836

Citations

54

Authors

33

Institutions

Publications per year

2017–2026

1

Parents

Publications

21

The size distribution of insertions and deletions in human and rodent pseudogenes suggests the logarithmic gap penalty for sequence alignment

Xun Gu, Wen‐Hsiung Li · Journal of Molecular Evolution · 1995 · 160 citations

, , +17

Empirical Analysis of Protein Insertions and Deletions Determining Parameters for the Correct Placement of Gaps in Protein Sequence Alignments

Mike Chang, Steven A. Benner · Journal of Molecular Biology · 2004 · 83 citations

, , +13

Comparative Cross-Species Alternative Splicing in Plants

Hadas Ner‐Gaon, Noam Leviatan, Eitan Rubin et al. · PLANT PHYSIOLOGY · 2007 · 79 citations · Full text

, , +11

Approximate Statistics of Gapped Alignments

Richard Mott, Roger Tribe · Journal of Computational Biology · 1999 · 75 citations

, , +13

ScanIndel: a hybrid framework for indel detection via gapped alignment, split reads and de novo assembly

Rendong Yang, Andrew C. Nelson, Christine Henzler et al. · Genome Medicine · 2015 · 45 citations · Full text

, , +15

1–5 of 21

Authors

54

  1. JL
    Jia Li

    Shanghai Institute of Materia Medica, China

    2 publications · 26 citations

    2

    h-index

  2. RB
    Ralf Bundschuh

    The Ohio State University, United States

    2 publications · 72 citations

    2

    h-index

  3. WM
    Webb Miller

    Pennsylvania State University, United States

    2 publications · 26 citations

    2

    h-index

  4. RG
    Robin Gras

    University of Windsor, Canada

    1 publications · 13 citations

    1

    h-index

  5. JW
    Junwen Wang

    University of Hong Kong, Hong Kong SAR China

    1 publications · 31 citations

    1

    h-index

1–5 of 54

Institutions

33

  1. Pennsylvania State University

    State College, United States

    2 h-index

    4 publications

    52 citations

  2. National Center for Biotechnology Information

    Bethesda, United States

    2 h-index

    4 publications

    62 citations

  3. Florida Atlantic University

    Boca Raton, United States

    2 h-index

    3 publications

    50 citations

  4. The University of Texas Health Science Center at Houston

    Houston, United States

    1 h-index

    2 publications

    320 citations

  5. Center for Human Genetics

    Bar Harbor, United States

    1 h-index

    1 publications

    160 citations

  6. The Ohio State University

    Columbus, United States

    1 h-index

    1 publications

    37 citations

  7. Vrije Universiteit Amsterdam

    Amsterdam, The Netherlands

    1 h-index

    2 publications

    38 citations

  8. Microsoft (United States)

    Redmond, United States

    1 h-index

    1 publications

    13 citations

1–8 of 33

Venues

  1. Journal of Computational Biology

    4 publications · 154 citations

    4

    h-index

  2. Computational Biology and Chemistry

    CBAC · 2 publications · 32 citations

    2

    h-index

  3. Bioinformatics

    2 publications · 73 citations

    2

    h-index

  4. Discrete Applied Mathematics

    1 publications · 35 citations

    1

    h-index

  5. Bulletin of Mathematical Biology

    1 publications · 26 citations

    1

    h-index

1–5