Concepedia

Gabaergic Synaptic Dysfunction

GABAergic Synaptic Dysfunction is a pathological alteration in synaptic transmission specifically attributable to impaired signaling at synapses utilizing gamma-aminobutyric acid (GABA) as their primary neurotransmitter, distinguished from other forms of synaptic dysfunction by its selective impact on inhibitory GABAergic circuits.

524

Publications

38.9K

Citations

3K

Authors

834

Institutions

Publications per year

2017–2026

159

Parents

Publications

524

Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes

Hsiao-Tuan Chao, Hongmei Chen, Rodney C. Samaco et al. · Nature · 2010 · 1.2K citations

, , +12

Decreased Hippocampal Inhibition and a Selective Loss of Interneurons in Experimental Epilepsy

Robert S. Sloviter · Science · 1987 · 1.1K citations

, , +17

Gene Expression for Glutamic Acid Decarboxylase Is Reduced Without Loss of Neurons in Prefrontal Cortex of Schizophrenics

Schahram Akbarian · Archives of General Psychiatry · 1995 · 1K citations

, , +17

GABA from reactive astrocytes impairs memory in mouse models of Alzheimer's disease

Seonmi Jo, Oleg Yarishkin, Yu Jin Hwang et al. · Nature Medicine · 2014 · 773 citations · Full text

, , +14

A decrease of reelin expression as a putative vulnerability factor in schizophrenia

Francesco Impagnatiello, Alessandro R. Guidotti, Christine Pesold et al. · Proceedings of the National Academy of Sciences · 1998 · 760 citations

, , +16

1–5 of 524

Authors

3K

  1. WL
    Wolfgang Löscher

    University of Veterinary Medicine Hannover, Foundation, Germany

    7 publications · 454 citations

    7

    h-index

  2. DM
    David M. Armstrong

    University of Bristol, United Kingdom

    6 publications · 248 citations

    6

    h-index

  3. RA
    Richard A.E. Edden

    Johns Hopkins University, United States

    6 publications · 398 citations

    6

    h-index

  4. DA
    David A. Lewis

    University of Pittsburgh, United States

    5 publications · 1.1K citations

    5

    h-index

  5. ER
    Esa R. Korpi

    University of Helsinki, Finland

    5 publications · 302 citations

    5

    h-index

1–5 of 3K

Institutions

834

  1. University of Pittsburgh

    Pittsburgh, United States

    15 h-index

    22 publications

    2K citations

  2. Inserm

    Paris, France

    13 h-index

    39 publications

    2.5K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    11 h-index

    43 publications

    2.6K citations

  4. Johns Hopkins University

    Baltimore, United States

    11 h-index

    20 publications

    1.5K citations

  5. University of Toronto

    Toronto, Canada

    10 h-index

    44 publications

    1.7K citations

  6. Harvard University

    Cambridge, United States

    10 h-index

    29 publications

    2K citations

  7. McLean Hospital

    Belmont, United States

    9 h-index

    33 publications

    2.2K citations

  8. Yale University

    New Haven, United States

    9 h-index

    35 publications

    2.9K citations

1–8 of 834

Venues

  1. Brain Research

    28 publications · 1.9K citations

    21

    h-index

  2. Neuroscience

    19 publications · 1.1K citations

    17

    h-index

  3. Neuroscience Letters

    17 publications · 1.2K citations

    16

    h-index

  4. Journal of Neuroscience

    16 publications · 2K citations

    15

    h-index

  5. Neuropharmacology

    16 publications · 693 citations

    14

    h-index

1–5