Concepedia

Futility Boundaries

Futility Boundary is a prespecified statistical threshold in sequential hypothesis testing that defines the condition under which continuing the trial is unlikely to yield a conclusive result, thereby warranting early termination for inefficacy.

14

Publications

1.3K

Citations

138

Authors

70

Institutions

Publications per year

2017–2026

6

Variants

Futility Boundary

Parents

Publications

14

Phase III Randomized Clinical Trial Comparing Tremelimumab With Standard-of-Care Chemotherapy in Patients With Advanced Melanoma

Antoni Ribas, Richard Kefford, Margaret Marshall et al. · Journal of Clinical Oncology · 2013 · 815 citations · Full text

, , +15

A multi-laboratory preclinical trial in rodents to assess treatment candidates for acute ischemic stroke

Patrick D. Lyden, Márcio A. Diniz, Francesca Bosetti et al. · Science Translational Medicine · 2023 · 64 citations

, , +15

Continuously updated network meta-analysis and statistical monitoring for timely decision-making

Adriani Nikolakopoulou, Dimitris Mavridis, Matthias Egger et al. · Statistical Methods in Medical Research · 2016 · 57 citations · Full text

, , +11

Design and Monitoring of Multi-Arm Multi-Stage Clinical Trials

Pranab Ghosh, Lingyun Liu, Pralay Senchaudhuri et al. · Biometrics · 2017 · 53 citations · Full text

, , +14

Phase 2 study of parsaclisib (INCB050465), a highly selective, next-generation PI3Kδ inhibitor, in relapsed or refractory diffuse large B-cell lymphoma (CITADEL-202)

Morton Coleman, David Belada, Olivier Casasnovas et al. · Leukemia & lymphoma/Leukemia and lymphoma · 2020 · 47 citations · Full text

, , +14

1–5 of 14

Authors

138

  1. GR
    Geraldine Rauch

    Heidelberg University, Germany

    2 publications · 60 citations

    2

    h-index

  2. MS
    Michael Smylie

    Bristol-Myers Squibb (United States), United States

    1 publications · 815 citations

    1

    h-index

  3. AM
    Andreia Morais

    Massachusetts General Hospital, United States

    1 publications · 64 citations

    1

    h-index

  4. GP
    Gerald P. Linette

    Washington University in St. Louis, United States

    1 publications · 815 citations

    1

    h-index

  5. SD
    Sebastián Díaz-Pérez

    University of Pennsylvania, United States

    1 publications · 64 citations

    1

    h-index

1–5 of 138

Institutions

70

  1. Harvard University

    Cambridge, United States

    2 h-index

    6 publications

    373 citations

  2. London Cancer

    London, United Kingdom

    1 h-index

    1 publications

    25 citations

  3. University of Massachusetts Boston

    Boston, United States

    1 h-index

    1 publications

    53 citations

  4. National Cerebral and Cardiovascular Center

    Osaka, Japan

    1 h-index

    2 publications

    38 citations

  5. University of Nebraska at Omaha

    Omaha, United States

    1 h-index

    2 publications

    46 citations

  6. National Institutes of Health

    Bethesda, United States

    1 h-index

    2 publications

    128 citations

  7. The University of Osaka

    Osaka, Japan

    1 h-index

    2 publications

    38 citations

  8. St Vincent's Hospital Sydney

    Darlinghurst, Australia

    1 h-index

    1 publications

    47 citations

1–8 of 70

Venues

  1. Journal of Clinical Oncology

    2 publications · 838 citations

    2

    h-index

  2. BMC Medical Research Methodology

    2 publications · 60 citations

    2

    h-index

  3. Clinical Trials

    2 publications · 42 citations

    2

    h-index

  4. Statistical Methods in Medical Research

    1 publications · 57 citations

    1

    h-index

  5. Statistics in Biopharmaceutical Research

    SBR · 1 publications · 29 citations

    1

    h-index

1–5