Concepedia

Fusion Efficiency Optimization

Fusion Efficiency Optimization is a methodological framework in hybridoma technology that systematically enhances the rate and viability of plasma cell-myeloma cell fusion through precise modulation of polyethylene glycol concentration, cell mixing ratios, and fusion protocols to maximize monoclonal antibody-producing hybrid cell yield.

19

Publications

531

Citations

94

Authors

26

Institutions

Publications per year

2017–2026

5

Parents

Publications

19

Determination of the optimal human cell lines for development of human hybridomas.

Paul G. Abrams, James A. Knost, G. Clarke et al. · The Journal of Immunology · 1983 · 82 citations · Full text

, , +12

Production of human-human hybridomas secreting antibody to sheep erythrocytes after <i>in vitro</i> immunization.

L E Strike, Bruce H. Devens, Robert L. Lundak · The Journal of Immunology · 1984 · 50 citations · Full text

, , +12

Improved fusion methods. IV. Technical aspects

Regine J. Westerwoudt · Journal of Immunological Methods · 1985 · 50 citations

, , +13

On chip electrofusion of single human B cells and mouse myeloma cells for efficient hybridoma generation

Evelien Kemna, Floor Wolbers, I. Vermes et al. · Electrophoresis · 2011 · 47 citations · Full text

, , +14

Complex Size and Surface Charge Determine Nucleic Acid Transfer by Fusogenic Liposomes

Marco Hoffmann, Nils Hersch, S. Gerlach et al. · International Journal of Molecular Sciences · 2020 · 32 citations · Full text

, , +15

1–5 of 19

Authors

94

  1. UZ
    U. Zimmermann

    University of Würzburg, Germany

    2 publications · 51 citations

    2

    h-index

  2. JH
    Jian He

    Guangxi Medical University, China

    1 publications · 11 citations

    1

    h-index

  3. JS
    Jessica Schmitt

    University of Würzburg, Germany

    1 publications · 24 citations

    1

    h-index

  4. XL
    Xinyao Lu

    Jiangnan University, China

    1 publications · 15 citations

    1

    h-index

  5. ZQ
    Zheng Qin Yin

    Southwest Hospital, China

    1 publications · 17 citations

    1

    h-index

1–5 of 94

Institutions

26

  1. Chongqing University

    Chongqing, China

    2 h-index

    7 publications

    154 citations

  2. University of Tsukuba

    Tsukuba, Japan

    1 h-index

    2 publications

    40 citations

  3. University of Twente

    Enschede, The Netherlands

    1 h-index

    4 publications

    188 citations

  4. Institut de Biosciences et Biotechnologies

    Pertuis, France

    1 h-index

    1 publications

    24 citations

  5. University of California, Riverside

    Riverside, United States

    1 h-index

    2 publications

    100 citations

  6. Chongqing Academy of Animal Science

    Chongqing, China

    1 h-index

    2 publications

    48 citations

  7. Analogic (United States)

    Peabody, United States

    1 h-index

    1 publications

    50 citations

  8. Tohoku University

    Sendai, Japan

    1 h-index

    3 publications

    66 citations

1–8 of 26

Venues

  1. Journal of Immunological Methods

    3 publications · 90 citations

    3

    h-index

  2. Hybridoma

    2 publications · 54 citations

    2

    h-index

  3. The Journal of Immunology

    JI · 2 publications · 132 citations

    2

    h-index

  4. Electrophoresis

    1 publications · 47 citations

    1

    h-index

  5. International Journal of Molecular Sciences

    IJMS · 1 publications · 32 citations

    1

    h-index

1–5