Concepedia

Functional Group Mimicry

Functional Group Mimicry is a nonclassical bioisosteric strategy in medicinal chemistry whereby a substituent or moiety functions as a bioisostere by emulating the electronic, steric, or pharmacophoric properties of a reference functional group despite differing in chemical structure.

4

Publications

199

Citations

16

Authors

7

Institutions

Publications per year

2017–2026

0

Parents

Publications

4

Hypervalent Iodine as a Terminal Oxidant in Wacker-Type Oxidation of Terminal Olefins to Methyl Ketones

Dipali A. Chaudhari, Rodney A. Fernandes · The Journal of Organic Chemistry · 2016 · 67 citations

, , +12

Structural Analysis of Silanediols as Transition-State-Analogue Inhibitors of the Benchmark Metalloprotease Thermolysin<sup>,</sup>

D.H. Juers, Jaeseung Kim, Brian W. Matthews et al. · Biochemistry · 2005 · 52 citations

, , +15

FRET Characterization of Complex Conformational Changes in a Large 16S Ribosomal RNA Fragment Site-Specifically Labeled Using Unnatural Base Pairs

Thomas Lavergne, Rajan Lamichhane, Denis A. Malyshev et al. · ACS Chemical Biology · 2016 · 51 citations

, , +16

Mimetic Form and Coloration in the Cerambycidae (Coleoptera)

E Gorton Linsley · Annals of the Entomological Society of America · 1959 · 29 citations

, , +8

Synthesis of <i>gem</i>-Difluorinated 1,3-Dienes via Synergistic Cu/Pd-Catalyzed Borodifluorovinylation of Alkynes

Wenyan Xu, Yujie Li, Tian‐Jun Gong et al. · Organic Letters · 2022 · 18 citations

, , +13

1–5 of 4

Authors

16

  1. FE
    Floyd E. Romesberg

    Scripps Research Institute, United States

    1 publications · 51 citations

    1

    h-index

  2. TL
    Thomas Lavergne

    Centre National de la Recherche Scientifique, France

    1 publications · 51 citations

    1

    h-index

  3. JR
    James R. Williamson

    Scripps Research Institute, United States

    1 publications · 51 citations

    1

    h-index

  4. DJ
    D.H. Juers

    Whitman College, United States

    1 publications · 52 citations

    1

    h-index

  5. RL
    Rajan Lamichhane

    Scripps Research Institute, United States

    1 publications · 51 citations

    1

    h-index

1–5 of 16

Institutions

7

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    1 h-index

    4 publications

    208 citations

  2. Indian Institute of Technology Bombay

    Mumbai, India

    1 h-index

    2 publications

    134 citations

  3. University of Oregon

    Eugene, United States

    1 h-index

    4 publications

    208 citations

  4. Scripps Research Institute

    San Diego, United States

    1 h-index

    9 publications

    459 citations

  5. State University of New York

    Albany, United States

    1 h-index

    4 publications

    208 citations

  6. University of California, Berkeley

    Berkeley, United States

    1 h-index

    1 publications

    29 citations

  7. Temple University

    Philadelphia, United States

    1 h-index

    4 publications

    208 citations

  8. University of Science and Technology of China

    Hefei, China

    1 publications

    18 citations

1–8 of 7

Venues

  1. ACS Chemical Biology

    1 publications · 51 citations

    1

    h-index

  2. The Journal of Organic Chemistry

    JOC · 1 publications · 67 citations

    1

    h-index

  3. 1

    h-index

  4. Biochemistry

    1 publications · 52 citations

    1

    h-index

  5. Organic Letters

    OL · 1 publications · 18 citations

1–5