Concepedia

Front-back Polarity

Front-Back Polarity is a cellular organization principle in cell motility that establishes an asymmetric distribution of signaling molecules, cytoskeletal components, and membrane protrusions along the cell axis, enabling directional movement by defining distinct leading and trailing edges.

15

Publications

792

Citations

76

Authors

36

Institutions

Publications per year

2017–2026

6

Parents

Publications

15

Segregation and activation of myosin IIB creates a rear in migrating cells

Miguel Vicente‐Manzanares, Margaret A. Koach, Leanna Whitmore et al. · The Journal of Cell Biology · 2008 · 227 citations · Full text

, , +17

An ezrin-rich, rigid uropod-like structure directs movement of amoeboid blebbing cells

Anna Lorentzen, Jeffrey C. Bamber, Amine Sadok et al. · Journal of Cell Science · 2011 · 124 citations

, , +17

Spontaneous polarization in eukaryotic gradient sensing: A mathematical model based on mutual inhibition of frontness and backness pathways

Atul Narang · Journal of Theoretical Biology · 2005 · 64 citations

, , +9

BPAG1e Maintains Keratinocyte Polarity through β4 Integrin–mediated Modulation of Rac 1 and Cofilin Activities

Kevin J. Hamill, Susan B. Hopkinson, Philip Debiase et al. · Molecular Biology of the Cell · 2009 · 62 citations

, , +16

Identifying Network Motifs that Buffer Front-to-Back Signaling in Polarized Neutrophils

Yanqin Wang, Chin‐Jen Ku, Elizabeth R. Zhang et al. · Cell Reports · 2013 · 48 citations · Full text

, , +16

1–5 of 15

Authors

76

  1. LA
    Leslie A. Rivera Rosado

    Center for Drug Evaluation and Research, United States

    2 publications · 32 citations

    2

    h-index

  2. JT
    Joy T. Yang

    Johns Hopkins University, United States

    2 publications · 32 citations

    2

    h-index

  3. TA
    Troy A. Horn

    Johns Hopkins University, United States

    2 publications · 32 citations

    2

    h-index

  4. CJ
    Christopher J. Marshall

    Institute of Cancer Research, United Kingdom

    1 publications · 124 citations

    1

    h-index

  5. PW
    Peng‐Ye Wang

    Institute of Physics, China

    1 publications · 19 citations

    1

    h-index

1–5 of 76

Institutions

36

  1. Johns Hopkins Medicine

    Baltimore, United States

    2 h-index

    6 publications

    112 citations

  2. Johns Hopkins University

    Baltimore, United States

    2 h-index

    10 publications

    160 citations

  3. Columbia University

    New York, United States

    1 h-index

    2 publications

    92 citations

  4. Peking University

    Beijing, China

    1 h-index

    2 publications

    38 citations

  5. Whitehead Institute for Biomedical Research

    Cambridge, United States

    1 h-index

    1 publications

    25 citations

  6. New York Structural Biology Center

    New York, United States

    1 h-index

    2 publications

    92 citations

  7. Biologie cellulaire et Cancer

    Paris, France

    1 h-index

    4 publications

    136 citations

  8. Cancer Research UK

    London, United Kingdom

    1 h-index

    4 publications

    496 citations

1–8 of 36

Venues

  1. Journal of Cell Science

    3 publications · 188 citations

    3

    h-index

  2. Cell Reports

    2 publications · 87 citations

    2

    h-index

  3. The Journal of Cell Biology

    JCB · 1 publications · 227 citations

    1

    h-index

  4. Nature Communications

    1 publications · 25 citations

    1

    h-index

  5. Small

    1 publications · 19 citations

    1

    h-index

1–5