Concepedia

Fragment Space

Fragment Space is a structured representation within chemical space analysis that consists of a collection of molecular fragments, serving as the foundational building blocks for de novo molecular design and compound optimization.

38

Publications

2.6K

Citations

125

Authors

54

Institutions

Publications per year

2017–2026

16

Parents

Publications

38

On the Art of Compiling and Using 'Drug‐Like' Chemical Fragment Spaces

Jörg Degen, Christof Gerlach, Andrea Zaliani et al. · ChemMedChem · 2008 · 637 citations

, , +13

Chemography:  The Art of Navigating in Chemical Space

Tudor I. Oprea, Johan Gottfries · Journal of Combinatorial Chemistry · 2001 · 359 citations

, , +17

Chemical fragments in real space: Definitions, properties, and energetic decompositions

Ángel Martín Pendás, M. A. Blanco, E. Francisco · Journal of Computational Chemistry · 2006 · 190 citations · Full text

, , +15

Enriching screening libraries with bioactive fragment space

Na Zhang, Hongtao Zhao · Bioorganic & Medicinal Chemistry Letters · 2016 · 140 citations · Full text

, , +11

Plane of Best Fit: A Novel Method to Characterize the Three-Dimensionality of Molecules

Nicholas C. Firth, Nathan Brown, Julian Blagg · Journal of Chemical Information and Modeling · 2012 · 133 citations · Full text

, , +10

1–5 of 38

Authors

125

  1. MR
    Matthias Rarey

    Universität Hamburg, Germany

    12 publications · 1K citations

    11

    h-index

  2. LB
    Louis Bellmann

    Universität Hamburg, Germany

    3 publications · 119 citations

    3

    h-index

  3. JR
    Jean‐Louis Reymond

    University of Bern, Switzerland

    3 publications · 148 citations

    3

    h-index

  4. JD
    Jörg Degen

    Universität Hamburg, Germany

    3 publications · 725 citations

    3

    h-index

  5. PP
    Patrick Penner

    Universität Hamburg, Germany

    2 publications · 105 citations

    2

    h-index

1–5 of 125

Institutions

54

  1. Universität Hamburg

    Hamburg, Germany

    11 h-index

    29 publications

    2.8K citations

  2. University of Bern

    Bern, Switzerland

    3 h-index

    7 publications

    352 citations

  3. Bayer (Germany)

    Leverkusen, Germany

    2 h-index

    2 publications

    659 citations

  4. Institute of Cancer Research

    London, United Kingdom

    2 h-index

    5 publications

    439 citations

  5. Université de Strasbourg

    Strasbourg, France

    2 h-index

    7 publications

    256 citations

  6. Roche (Switzerland)

    Basel, Switzerland

    2 h-index

    5 publications

    187 citations

  7. University of Dundee

    Dundee, United Kingdom

    1 h-index

    2 publications

    40 citations

  8. Central China Normal University

    Wuhan, China

    1 h-index

    8 publications

    480 citations

1–8 of 54

Venues

  1. Journal of Chemical Information and Modeling

    JCIM · 16 publications · 764 citations

    14

    h-index

  2. Journal of Computer-Aided Molecular Design

    4 publications · 85 citations

    4

    h-index

  3. ChemMedChem

    3 publications · 754 citations

    3

    h-index

  4. Bioorganic & Medicinal Chemistry Letters

    2 publications · 162 citations

    2

    h-index

  5. ACS Medicinal Chemistry Letters

    1 publications · 33 citations

    1

    h-index

1–5