Concepedia

Force-induced Allostery

Force-Induced Allostery is a biophysical phenomenon in which mechanical force applied to a biomolecule at a specific site induces conformational or functional changes at a distant, non-local site, thereby modulating its activity or binding properties through an allosteric mechanism directed by external mechanical perturbation.

7

Publications

445

Citations

49

Authors

21

Institutions

Publications per year

2017–2026

4

Parents

Publications

7

Catch-Bond Model Derived from Allostery Explains Force-Activated Bacterial Adhesion

Wendy E. Thomas, Manu Forero-Shelton, Olga Yakovenko et al. · Biophysical Journal · 2005 · 206 citations · Full text

, , +14

Force-dependent allostery of the α-catenin actin-binding domain controls adherens junction dynamics and functions

Noboru Ishiyama, Ritu Sarpal, Megan Wood et al. · Nature Communications · 2018 · 106 citations · Full text

, , +17

A Lupus-Associated Mac-1 Variant Has Defects in Integrin Allostery and Interaction with Ligands under Force

Florencia Rosetti, Yunfeng Chen, Mehmet Şen et al. · Cell Reports · 2015 · 76 citations · Full text

, , +17

Prediction of Catch-Slip Bond Transition of Kindlin2/β3 Integrin via Steered Molecular Dynamics Simulation

Yan Zhang, Zhanyi Lin, Ying Fang et al. · Journal of Chemical Information and Modeling · 2020 · 22 citations

, , +17

Salt bridge interactions within the β<sub>2</sub> integrin α<sub>7</sub> helix mediate force‐induced binding and shear resistance ability

Xiao Zhang, Linda Li, Ning Li et al. · FEBS Journal · 2017 · 12 citations · Full text

, , +17

1–5 of 7

Authors

49

  1. JW
    Jianhua Wu

    South China University of Technology, China

    2 publications · 34 citations

    2

    h-index

  2. YF
    Ying Fang

    South China University of Technology, China

    2 publications · 34 citations

    2

    h-index

  3. JO
    Jun Ohnuki

    Waseda University, Japan

    1 publications · 11 citations

    1

    h-index

  4. XC
    Xavier Culleré

    Harvard University, United States

    1 publications · 76 citations

    1

    h-index

  5. SC
    Shenbao Chen

    Institute of Mechanics, China

    1 publications · 12 citations

    1

    h-index

1–5 of 49

Institutions

21

  1. South China University of Technology

    Guangzhou, China

    2 h-index

    7 publications

    114 citations

  2. University of Chinese Academy of Sciences

    Beijing, China

    1 h-index

    8 publications

    96 citations

  3. Harvard University

    Cambridge, United States

    1 h-index

    2 publications

    152 citations

  4. Princess Margaret Cancer Centre

    Toronto, Canada

    1 h-index

    3 publications

    318 citations

  5. Chinese Academy of Sciences

    Beijing, China

    1 h-index

    8 publications

    96 citations

  6. University of Washington

    Seattle, United States

    1 h-index

    7 publications

    1.4K citations

  7. University of Illinois Urbana-Champaign

    Urbana, United States

    1 h-index

    2 publications

    212 citations

  8. University Health Network

    Toronto, Canada

    1 h-index

    2 publications

    212 citations

1–8 of 21

Venues

  1. Nature Communications

    1 publications · 106 citations

    1

    h-index

  2. Scientific Reports

    1 publications · 12 citations

    1

    h-index

  3. Biophysical Journal

    1 publications · 206 citations

    1

    h-index

  4. Physical review. E

    PRE · 1 publications · 11 citations

    1

    h-index

  5. FEBS Journal

    1 publications · 12 citations

    1

    h-index

1–5