Concepedia

Folding Cooperativity

Folding Cooperativity is a theoretical construct in protein folding thermodynamics that characterizes the extent to which the folding of a macromolecule occurs in an all-or-none manner, where the stabilization of tertiary structure arises from highly interdependent conformational transitions rather than isolated local interactions.

147

Publications

7.4K

Citations

438

Authors

184

Institutions

Publications per year

2017–2026

12

Variants

Cooperative Folding

Parents

Publications

147

Experiment and theory highlight role of native state topology in SH3 folding.

David Baker, David S. Riddle, Viara P. Grantcharova et al. · Nature Structural Biology · 1999 · 385 citations

, , +16

Protein Simulations with an Optimized Water Model: Cooperative Helix Formation and Temperature-Induced Unfolded State Collapse

Robert B. Best, Jeetain Mittal · The Journal of Physical Chemistry B · 2010 · 269 citations

, , +14

The folding cooperativity of a protein is controlled by its chain topology

Elizabeth A. Shank, Ciro Cecconi, Jesse Dill et al. · Nature · 2010 · 247 citations · Full text

, , +14

Cooperativity in Amide Hydrogen Bonding Chains:  Implications for Protein-Folding Models

Nadya Kobko, Lilly-Rose Paraskevas, J. J. Dannenberg · Journal of the American Chemical Society · 2001 · 176 citations

, , +17

Cooperativity Principles in Protein Folding

Hue Sun Chan, Seishi Shimizu, Hüseyin Kaya · Methods in enzymology on CD-ROM/Methods in enzymology · 2004 · 175 citations

, , +14

1–5 of 147

Authors

438

  1. HS
    Hue Sun Chan

    University of Toronto, Canada

    5 publications · 417 citations

    5

    h-index

  2. MO
    Mikael Oliveberg

    Stockholm University, Sweden

    4 publications · 204 citations

    4

    h-index

  3. DT
    D. Thirumalai

    University of Maryland, College Park, United States

    4 publications · 312 citations

    4

    h-index

  4. KA
    Ken A. Dill

    University of California, San Francisco, United States

    4 publications · 273 citations

    4

    h-index

  5. VM
    Víctor Muñoz

    University of Maryland, College Park, United States

    4 publications · 89 citations

    4

    h-index

1–5 of 438

Institutions

184

  1. University of Maryland, College Park

    College Park, United States

    8 h-index

    18 publications

    985 citations

  2. Johns Hopkins University

    Baltimore, United States

    8 h-index

    16 publications

    945 citations

  3. University of Cambridge

    Cambridge, United Kingdom

    7 h-index

    13 publications

    1.2K citations

  4. Nanjing University

    Nanjing, China

    5 h-index

    22 publications

    579 citations

  5. University of Toronto

    Toronto, Canada

    5 h-index

    10 publications

    697 citations

  6. University of Pennsylvania

    Philadelphia, United States

    5 h-index

    21 publications

    1.9K citations

  7. Tata Institute of Fundamental Research

    Mumbai, India

    5 h-index

    9 publications

    208 citations

  8. University of California, Santa Barbara

    Santa Barbara, United States

    5 h-index

    10 publications

    355 citations

1–8 of 184

Venues

  1. Journal of Molecular Biology

    JMB · 17 publications · 974 citations

    15

    h-index

  2. Biochemistry

    12 publications · 448 citations

    11

    h-index

  3. Journal of the American Chemical Society

    JACS · 10 publications · 516 citations

    10

    h-index

  4. Proteins Structure Function and Bioinformatics

    9 publications · 529 citations

    9

    h-index

  5. Biophysical Journal

    8 publications · 428 citations

    8

    h-index

1–5