Concepedia

Fmoc Protection

Fmoc Protection is a protecting-group strategy in organic synthesis wherein the 9-fluorenylmethoxycarbonyl (Fmoc) group is selectively introduced to shield amine functionalities, distinguished by its base-labile cleavage mechanism that enables orthogonal deprotection in peptide synthesis.

380

Publications

15.6K

Citations

1.2K

Authors

375

Institutions

Publications per year

2017–2026

36

Parents

Publications

380

New trends in the chemistry of α-fluorinated ethers, thioethers, amines and phosphines

Baptiste Manteau, Sergiy Pazenok, Jean‐Pierre Vors et al. · Journal of Fluorine Chemistry · 2009 · 387 citations

, , +9

Pseudo-Prolines as a Solubilizing, Structure-Disrupting Protection Technique in Peptide Synthesis

Torsten Wöhr, Franck Olivier Wahl, Adel Nefzi et al. · Journal of the American Chemical Society · 1996 · 341 citations · Full text

, , +14

SOLID PHASE SYNTHESIS WITHOUT REPETITIVE ACIDOLYSIS

Johannes Meienhofer, Michinori Waki, EDGAR P. HEIMRE et al. · International journal of peptide & protein research · 1979 · 312 citations

, , +14

A Versatile Amino Acid Analogue of the Solvatochromic Fluorophore 4-<i>N,N</i>-Dimethylamino-1,8-naphthalimide: A Powerful Tool for the Study of Dynamic Protein Interactions

Galen S. Loving, Barbara Imperiali · Journal of the American Chemical Society · 2008 · 246 citations · Full text

, , +17

HBTU activation for automated Fmoc solid-phase peptide synthesis.

Cynthia G. Fields, Donna Lloyd, Robyn L. Macdonald et al. · PubMed · 1992 · 230 citations

, , +10

1–5 of 380

Authors

1.2K

  1. FA
    Fernando Alberício

    Universitat de Barcelona, Spain

    28 publications · 1.2K citations

    24

    h-index

  2. GB
    George Bárány

    University of Minnesota, United States

    8 publications · 438 citations

    8

    h-index

  3. EG
    Ernest Giralt

    Universitat de Barcelona, Spain

    8 publications · 323 citations

    8

    h-index

  4. TR
    Terrence R. Burke

    National Institutes of Health, United States

    6 publications · 239 citations

    6

    h-index

  5. HK
    Horst Kunz

    Johannes Gutenberg University Mainz, Germany

    5 publications · 191 citations

    5

    h-index

1–5 of 1.2K

Institutions

375

  1. Universitat de Barcelona

    Barcelona, Spain

    20 h-index

    92 publications

    4K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    12 h-index

    49 publications

    2.2K citations

  3. University of Minnesota

    Minneapolis, United States

    12 h-index

    45 publications

    2.9K citations

  4. Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine

    Madrid, Spain

    9 h-index

    18 publications

    633 citations

  5. ETH Zurich

    Zurich, Switzerland

    9 h-index

    20 publications

    833 citations

  6. University of KwaZulu-Natal

    Durban, South Africa

    9 h-index

    21 publications

    754 citations

  7. Johannes Gutenberg University Mainz

    Mainz, Germany

    7 h-index

    16 publications

    576 citations

  8. Institute for Research in Biomedicine

    Barcelona, Spain

    7 h-index

    28 publications

    846 citations

1–8 of 375

Venues

  1. The Journal of Organic Chemistry

    JOC · 43 publications · 2K citations

    26

    h-index

  2. Tetrahedron Letters

    44 publications · 1.5K citations

    23

    h-index

  3. 20

    h-index

  4. Organic Letters

    OL · 26 publications · 994 citations

    20

    h-index

  5. Journal of Peptide Science

    21 publications · 738 citations

    18

    h-index

1–5