Concepedia

Flexible Fitting

Flexible Fitting is a computational method in integrative structural biology that refines atomic models into cryo-electron microscopy density maps by allowing conformational changes to accommodate structural flexibility, thereby distinguishing it from rigid-body fitting approaches.

89

Publications

7.3K

Citations

336

Authors

159

Institutions

Publications per year

2017–2026

27

Variants

Flexible Molecular Fitting

Parents

Publications

89

Flexible Fitting of Atomic Structures into Electron Microscopy Maps Using Molecular Dynamics

Leonardo G. Trabuco, Elizabeth Villa, Kakoli Mitra et al. · Structure · 2008 · 915 citations · Full text

, , +14

FlexMix Version 2: Finite Mixtures with Concomitant Variables and Varying and Constant Parameters

Bettina Grün, Friedrich Leisch · Journal of Statistical Software · 2008 · 455 citations · Full text

, , +15

<i>Namdinator</i> – automatic molecular dynamics flexible fitting of structural models into cryo-EM and crystallography experimental maps

R.T. Kidmose, Jonathan Juhl, Poul Nissen et al. · IUCrJ · 2019 · 434 citations · Full text

, , +17

Molecular dynamics flexible fitting: A practical guide to combine cryo-electron microscopy and X-ray crystallography

Leonardo G. Trabuco, Elizabeth Villa, Eduard Schreiner et al. · Methods · 2009 · 371 citations · Full text

, , +17

Near-atomic resolution structural model of the yeast 26S proteasome

Florian Beck, Pia Unverdorben, Stefan Bohn et al. · Proceedings of the National Academy of Sciences · 2012 · 259 citations · Full text

, , +17

1–5 of 89

Authors

336

  1. FT
    Florence Tama

    RIKEN Center for Computational Science, Japan

    14 publications · 1.1K citations

    14

    h-index

  2. KS
    Klaus Schulten

    University of Illinois Urbana-Champaign, United States

    10 publications · 2K citations

    10

    h-index

  3. OM
    Osamu Miyashita

    RIKEN Center for Computational Science, Japan

    8 publications · 737 citations

    8

    h-index

  4. MT
    Maya Topf

    Birkbeck, University of London, United Kingdom

    7 publications · 485 citations

    7

    h-index

  5. EV
    Elizabeth Villa

    University of California San Diego, United States

    5 publications · 1.8K citations

    5

    h-index

1–5 of 336

Institutions

159

  1. University of Illinois Urbana-Champaign

    Urbana, United States

    11 h-index

    36 publications

    5.9K citations

  2. Birkbeck, University of London

    London, United Kingdom

    7 h-index

    17 publications

    1.5K citations

  3. University of Arizona

    Tucson, United States

    7 h-index

    17 publications

    941 citations

  4. Universidad Autónoma de Madrid

    Madrid, Spain

    6 h-index

    17 publications

    1.1K citations

  5. Institute of Structural and Molecular Biology

    London, United Kingdom

    6 h-index

    13 publications

    1.2K citations

  6. RIKEN Center for Computational Science

    Kobe, Japan

    6 h-index

    13 publications

    466 citations

  7. Howard Hughes Medical Institute

    Chevy Chase, United States

    6 h-index

    10 publications

    2.9K citations

  8. Centro Nacional de Biotecnología

    Madrid, Spain

    6 h-index

    39 publications

    1.9K citations

1–8 of 159

Venues

  1. Journal of Structural Biology

    12 publications · 985 citations

    12

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 5 publications · 773 citations

    5

    h-index

  3. Biophysical Journal

    5 publications · 330 citations

    5

    h-index

  4. Structure

    4 publications · 1K citations

    4

    h-index

  5. Journal of Molecular Biology

    JMB · 3 publications · 310 citations

    3

    h-index

1–5