Concepedia

Flap Endonuclease 1 Processing

Flap Endonuclease 1 Processing is a molecular mechanism in DNA replication that specifically refers to the enzymatic cleavage of 5' overhanging flaps generated during Okazaki fragment maturation, whereby Flap Endonuclease 1 recognizes and incises displaced single-stranded DNA flaps to enable ligation of adjacent fragments.

167

Publications

10.4K

Citations

719

Authors

208

Institutions

Publications per year

2017–2026

33

Parents

Publications

167

HIV-1 Genome Nuclear Import Is Mediated by a Central DNA Flap

Véronique Zennou, Caroline Petit, Denise Guétard et al. · Cell · 2000 · 819 citations

, , +13

Human Flap Endonuclease Structures, DNA Double-Base Flipping, and a Unified Understanding of the FEN1 Superfamily

Susan E. Tsutakawa, Scott Classen, B.R. Chapados et al. · Cell · 2011 · 294 citations · Full text

, , +9

Werner syndrome protein interacts with human flap endonuclease 1 and stimulates its cleavage activity

Cayetano von Kobbe, Joshua A. Sommers, Parimal Karmakar et al. · The EMBO Journal · 2001 · 257 citations · Full text

, , +8

Structural basis for recruitment of human flap endonuclease 1 to PCNA

Shigeru Sakurai, Ken Kitano, Hiroto Yamaguchi et al. · The EMBO Journal · 2004 · 242 citations · Full text

, , +8

Identification and Characterization of the Human Mus81-Eme1 Endonuclease

Alberto Ciccia, Angelos Constantinou, Stephen C. West · Journal of Biological Chemistry · 2003 · 208 citations · Full text

, , +13

1–5 of 167

Authors

719

  1. RA
    Robert A. Bambara

    University of Rochester, United States

    24 publications · 1.7K citations

    23

    h-index

  2. BS
    Binghui Shen

    City Of Hope National Medical Center, United States

    17 publications · 1.3K citations

    15

    h-index

  3. JA
    Jane A. Grasby

    University of Sheffield, United Kingdom

    10 publications · 644 citations

    10

    h-index

  4. JL
    Judith L. Campbell

    California Institute of Technology, United States

    9 publications · 518 citations

    9

    h-index

  5. YL
    Yuan Liu

    Florida International University, United States

    9 publications · 619 citations

    9

    h-index

1–5 of 719

Institutions

208

  1. University of Rochester

    Rochester, United States

    21 h-index

    65 publications

    4.6K citations

  2. City Of Hope National Medical Center

    Duarte, United States

    15 h-index

    71 publications

    4.9K citations

  3. National Institutes of Health

    Bethesda, United States

    12 h-index

    55 publications

    6.4K citations

  4. National Institute on Aging

    Baltimore, United States

    12 h-index

    47 publications

    4.5K citations

  5. University of Sheffield

    Sheffield, United Kingdom

    11 h-index

    59 publications

    3.1K citations

  6. California Institute of Technology

    Pasadena, United States

    10 h-index

    14 publications

    880 citations

  7. University of Zurich

    Zurich, Switzerland

    8 h-index

    45 publications

    3.6K citations

  8. National Institute of Environmental Health Sciences

    Durham, United States

    6 h-index

    36 publications

    3.3K citations

1–8 of 208

Venues

  1. Journal of Biological Chemistry

    JBC · 49 publications · 3.3K citations

    34

    h-index

  2. Nucleic Acids Research

    16 publications · 563 citations

    16

    h-index

  3. Biochemistry

    6 publications · 356 citations

    6

    h-index

  4. Journal of Molecular Biology

    JMB · 5 publications · 182 citations

    5

    h-index

  5. The EMBO Journal

    5 publications · 620 citations

    5

    h-index

1–5