Concepedia

First-pass Effect Assessment

First-Pass Effect Assessment is a pharmacokinetic evaluation method that quantifies the extent of presystemic metabolism or clearance of a drug following oral administration before it reaches the systemic circulation.

118

Publications

6.2K

Citations

825

Authors

350

Institutions

Publications per year

2017–2026

45

Parents

Publications

118

First Pass Effect

Osama O. Zaidat, Alicia C. Castonguay, Italo Linfante et al. · Stroke · 2018 · 662 citations · Full text

, , +17

Midazolam kinetics

Hannu Allonen, G. Ziegler, Ulrich Klotz · Clinical Pharmacology & Therapeutics · 1981 · 288 citations

, , +12

Influence of First-Pass Effect on Availability of Drugs on Oral Administration

M. Gibaldi, R N Boyes, Stuart Feldman · Journal of Pharmaceutical Sciences · 1971 · 272 citations

, , +14

Clearance of Thrombin from Circulation in Rabbits by High-affinity Binding Sites on Endothelium

Pete Lollar, Whyte G. Owen · Journal of Clinical Investigation · 1980 · 201 citations · Full text

, , +11

True First-Pass Effect

Omid Nikoubashman, Sven Dekeyzer, Alexander Riabikin et al. · Stroke · 2019 · 191 citations · Full text

, , +16

1–5 of 118

Authors

825

  1. RG
    Raul G. Nogueira

    Emory University, United States

    5 publications · 822 citations

    5

    h-index

  2. BG
    Benjamin Gory

    Inserm, France

    4 publications · 281 citations

    4

    h-index

  3. AJ
    André J. Jackson

    Center for Drug Evaluation and Research, United States

    4 publications · 93 citations

    4

    h-index

  4. TN
    Thanh N. Nguyen

    Boston Medical Center, United States

    4 publications · 775 citations

    4

    h-index

  5. EV
    E von Möllendorff

    Roche (United States), United States

    3 publications · 227 citations

    3

    h-index

1–5 of 825

Institutions

350

  1. Emory University

    Atlanta, United States

    4 h-index

    14 publications

    736 citations

  2. University of California, Los Angeles

    Los Angeles, United States

    4 h-index

    8 publications

    414 citations

  3. Inserm

    Paris, France

    4 h-index

    27 publications

    1.6K citations

  4. Hospital Clínic de Barcelona

    Barcelona, Spain

    4 h-index

    14 publications

    269 citations

  5. Imagerie Adaptative Diagnostique et Interventionnelle

    Vandœuvre-lès-Nancy, France

    3 h-index

    5 publications

    431 citations

  6. Azienda Ospedaliero-Universitaria Careggi

    Florence, Italy

    3 h-index

    9 publications

    491 citations

  7. Neurological Surgery

    Rockville Centre, United States

    3 h-index

    6 publications

    219 citations

  8. Université de Lorraine

    Nancy, France

    3 h-index

    4 publications

    337 citations

1–8 of 350

Venues

  1. PubMed

    Repository · 12 publications · 498 citations

    12

    h-index

  2. Journal of NeuroInterventional Surgery

    JNIS · 11 publications · 470 citations

    10

    h-index

  3. Drug Metabolism and Disposition

    6 publications · 263 citations

    6

    h-index

  4. 5

    h-index

  5. Interventional Neuroradiology

    IN · 5 publications · 101 citations

    5

    h-index

1–5