Concepedia

Fingolimod Therapy

Fingolimod Therapy is a pharmacological treatment modality within the class of disease-modifying therapies for multiple sclerosis, distinguished by its mechanism of action as a sphingosine-1-phosphate receptor modulator that sequesters lymphocytes in lymph nodes to reduce autoimmune infiltration into the central nervous system.

769

Publications

41.8K

Citations

4.4K

Authors

1.4K

Institutions

Publications per year

2017–2026

378

Variants

Fingolimod Treatment

Parents

Publications

769

A Placebo-Controlled Trial of Oral Fingolimod in Relapsing Multiple Sclerosis

Ludwig Kappos, Ernst‐Wilhelm Radue, Paul O’Connor et al. · New England Journal of Medicine · 2010 · 2.6K citations · Full text

, , +14

Oral Fingolimod or Intramuscular Interferon for Relapsing Multiple Sclerosis

Jeffrey A. Cohen, Frederik Barkhof, Hans‐Peter Hartung et al. · New England Journal of Medicine · 2010 · 2.2K citations · Full text

, , +15

Siponimod versus placebo in secondary progressive multiple sclerosis (EXPAND): a double-blind, randomised, phase 3 study

Ludwig Kappos, Amit Bar‐Or, Bruce Cree et al. · The Lancet · 2018 · 925 citations

, , +9

Safety and efficacy of fingolimod in patients with relapsing-remitting multiple sclerosis (FREEDOMS II): a double-blind, randomised, placebo-controlled, phase 3 trial

Peter A. Calabresi, Ernst-Wilhelm Radüe, Douglas S. Goodin et al. · The Lancet Neurology · 2014 · 822 citations

, , +7

FTY720 (fingolimod) efficacy in an animal model of multiple sclerosis requires astrocyte sphingosine 1-phosphate receptor 1 (S1P <sub>1</sub> ) modulation

Ji Woong Choi, Shannon E. Gardell, Deron R. Herr et al. · Proceedings of the National Academy of Sciences · 2010 · 578 citations · Full text

, , +17

1–5 of 769

Authors

4.4K

  1. LK
    Ludwig Kappos

    University Hospital of Basel, Switzerland

    56 publications · 10.7K citations

    34

    h-index

  2. HB
    Helmut Butzkueven

    The University of Melbourne, Australia

    23 publications · 2K citations

    18

    h-index

  3. RA
    Raed Alroughani

    Amiri Hospital, Kuwait

    20 publications · 1.1K citations

    17

    h-index

  4. JK
    Jens Kühle

    University Hospital of Basel, Switzerland

    16 publications · 1.3K citations

    15

    h-index

  5. XM
    Xavier Montalbán

    Vall d'Hebron Hospital Universitari, Spain

    16 publications · 4.8K citations

    15

    h-index

1–5 of 4.4K

Institutions

1.4K

  1. Novartis (Switzerland)

    Basel, Switzerland

    45 h-index

    366 publications

    36.8K citations

  2. University Hospital of Basel

    Basel, Switzerland

    33 h-index

    153 publications

    17.8K citations

  3. Novartis (United States)

    New York, United States

    28 h-index

    110 publications

    12.1K citations

  4. Cleveland Clinic

    Cleveland, United States

    23 h-index

    96 publications

    9.7K citations

  5. University of Basel

    Basel, Switzerland

    19 h-index

    64 publications

    11.1K citations

  6. Heinrich Heine University Düsseldorf

    Düsseldorf, Germany

    19 h-index

    72 publications

    5.4K citations

  7. Montreal Neurological Institute and Hospital

    Montreal, Canada

    19 h-index

    58 publications

    9.5K citations

  8. University of California, San Francisco

    San Francisco, United States

    16 h-index

    38 publications

    5.4K citations

1–8 of 1.4K

Venues

  1. Multiple Sclerosis Journal

    MSJ · 65 publications · 3.3K citations

    33

    h-index

  2. Neurology

    39 publications · 3.7K citations

    30

    h-index

  3. Multiple Sclerosis and Related Disorders

    55 publications · 1.4K citations

    21

    h-index

  4. Neurology Neuroimmunology & Neuroinflammation

    21 publications · 787 citations

    18

    h-index

  5. PLoS ONE

    25 publications · 1K citations

    18

    h-index

1–5