Concepedia

Fed-fasted Comparison

Fed-Fasted Comparison is a pharmacokinetic evaluation method that compares the absorption, distribution, metabolism, and excretion of a test product under fed and fasted physiological conditions to assess food effect on drug bioavailability.

70

Publications

2.8K

Citations

382

Authors

142

Institutions

Publications per year

2017–2026

11

Parents

Publications

70

Apixaban, an oral, direct factor <scp>X</scp>a inhibitor: single dose safety, pharmacokinetics, pharmacodynamics and food effect in healthy subjects

Charles Frost, Jessie J. Wang, Sunil Nepal et al. · British Journal of Clinical Pharmacology · 2012 · 363 citations · Full text

, , +13

Pharmacokinetics and bioavailability of α-, γ- and δ-tocotrienols under different food status

Siew Ping Yap, Kah Hay Yuen, Jia Woei Wong · Journal of Pharmacy and Pharmacology · 2001 · 192 citations · Full text

, , +14

Less food, less hunger: reports of appetite and symptoms in a controlled study of a protein-sparing modified fast.

Thomas A. Wadden, A. J. Stunkard, Sally Day et al. · PubMed · 1987 · 103 citations

, , +15

Resolving the physiological conditions in bioavailability and bioequivalence studies: Comparison of fasted and fed state

Felix Schneider, Michael Grimm, Mirko Koziolek et al. · European Journal of Pharmaceutics and Biopharmaceutics · 2016 · 94 citations

, , +14

The Effect of Different Meal Types on the Pharmacokinetics of Darunavir (TMC114)/Ritonavir in HIV‐Negative Healthy Volunteers

Vanitha Sekar, Dries Kestens, Sabrina Spinosa‐Guzman et al. · The Journal of Clinical Pharmacology · 2007 · 94 citations

, , +17

1–5 of 70

Authors

382

  1. GF
    Georg Ferber

    St George's, University of London, United Kingdom

    2 publications · 112 citations

    2

    h-index

  2. RM
    Richard M. W. Hoetelmans

    Slotervaartziekenhuis, Netherlands

    2 publications · 134 citations

    2

    h-index

  3. JA
    Jay Ariyawansa

    Janssen (United States), United States

    2 publications · 28 citations

    2

    h-index

  4. DD
    Damayanthi Devineni

    Janssen (Belgium), Belgium

    2 publications · 31 citations

    2

    h-index

  5. AJ
    A. John Camm

    St George's, University of London, United Kingdom

    2 publications · 112 citations

    2

    h-index

1–5 of 382

Institutions

142

  1. Novartis (Switzerland)

    Basel, Switzerland

    3 h-index

    8 publications

    131 citations

  2. Pfizer (United States)

    New York, United States

    3 h-index

    5 publications

    176 citations

  3. Janssen (Belgium)

    Beerse, Belgium

    2 h-index

    7 publications

    254 citations

  4. Merck & Co., Inc., Rahway, NJ, USA (United States)

    Rahway, United States

    2 h-index

    17 publications

    385 citations

  5. Janssen (United States)

    Hopewell, United States

    2 h-index

    7 publications

    124 citations

  6. Harvard University

    Cambridge, United States

    2 h-index

    3 publications

    115 citations

  7. Research Triangle Park Foundation

    Durham, United States

    2 h-index

    8 publications

    156 citations

  8. St. Luke's-Roosevelt Hospital Center

    New York, United States

    2 h-index

    6 publications

    288 citations

1–8 of 142

Venues

  1. The Journal of Clinical Pharmacology

    15 publications · 534 citations

    14

    h-index

  2. Clinical Pharmacology in Drug Development

    CPDD · 6 publications · 138 citations

    6

    h-index

  3. British Journal of Clinical Pharmacology

    BJCP · 5 publications · 499 citations

    5

    h-index

  4. Clinical Therapeutics

    4 publications · 97 citations

    4

    h-index

  5. 4

    h-index

1–5