Concepedia

Fancd2-fanci Complex

The FANCD2-FANCI Complex is a heterodimeric protein complex within the Fanconi anemia DNA repair pathway that serves as a central activation scaffold by undergoing monoubiquitination in response to interstrand crosslinks, thereby recruiting downstream effector proteins for DNA damage repair.

272

Publications

20.4K

Citations

1.5K

Authors

464

Institutions

Publications per year

2017–2026

48

Parents

Publications

272

Identification of the FANCI Protein, a Monoubiquitinated FANCD2 Paralog Required for DNA Repair

Agata Smogorzewska, Shuhei Matsuoka, Patrizia Vinciguerra et al. · Cell · 2007 · 718 citations · Full text

, , +14

The Fanconi Anemia Pathway Promotes Replication-Dependent DNA Interstrand Cross-Link Repair

Puck Knipscheer, Markus Räschle, Agata Smogorzewska et al. · Science · 2009 · 529 citations

, , +17

Convergence of the Fanconi Anemia and Ataxia Telangiectasia Signaling Pathways

Toshiyasu Taniguchi, Irene García-Higuera, Bo Xu et al. · Cell · 2002 · 457 citations · Full text

, , +13

Positional Cloning of a Novel Fanconi Anemia Gene, FANCD2

Cynthia Timmers, Toshiyasu Taniguchi, James Hejna et al. · Molecular Cell · 2001 · 409 citations · Full text

, , +11

Hematologic abnormalities in Fanconi anemia: an International Fanconi Anemia Registry study [see comments]

A Butturini, Gale Rp, PC Verlander et al. · Blood · 1994 · 384 citations · Full text

, , +14

1–5 of 272

Authors

1.5K

  1. AD
    Alan D. D’Andrea

    Dana-Farber Cancer Institute, United States

    20 publications · 3.2K citations

    19

    h-index

  2. HJ
    Hans Joenje

    Amsterdam UMC Location Vrije Universiteit Amsterdam, Netherlands

    17 publications · 1.5K citations

    17

    h-index

  3. MG
    Markus Grompe

    Oregon Health & Science University, United States

    14 publications · 1.4K citations

    13

    h-index

  4. MT
    Minoru Takata

    Kyoto University, Japan

    12 publications · 1.3K citations

    12

    h-index

  5. AD
    Arleen D. Auerbach

    Rockefeller University, United States

    12 publications · 1K citations

    12

    h-index

1–5 of 1.5K

Institutions

464

  1. Dana-Farber Cancer Institute

    Boston, United States

    24 h-index

    108 publications

    13.9K citations

  2. Harvard University

    Cambridge, United States

    23 h-index

    99 publications

    14K citations

  3. Oregon Health & Science University

    Portland, United States

    21 h-index

    96 publications

    10K citations

  4. Kyoto University

    Kyoto, Japan

    16 h-index

    62 publications

    6.5K citations

  5. Rockefeller University

    New York, United States

    15 h-index

    56 publications

    6.4K citations

  6. University of Würzburg

    Würzburg, Germany

    11 h-index

    24 publications

    2.1K citations

  7. Yale University

    New Haven, United States

    11 h-index

    46 publications

    3.2K citations

  8. The University of Texas MD Anderson Cancer Center

    Houston, United States

    11 h-index

    53 publications

    3.9K citations

1–8 of 464

Venues

  1. Blood

    37 publications · 4.1K citations

    34

    h-index

  2. Cell Reports

    12 publications · 739 citations

    12

    h-index

  3. Nucleic Acids Research

    11 publications · 539 citations

    11

    h-index

  4. Journal of Biological Chemistry

    JBC · 10 publications · 637 citations

    10

    h-index

  5. Human Genetics

    10 publications · 474 citations

    10

    h-index

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