Concepedia

Fab Display

Fab Display is a phage display technique that involves the expression of Fab (antigen-binding fragment) antibodies on the surface of bacteriophages, where the Fab fragment—comprising the variable and constant regions of the heavy and light chains—is genetically fused to a phage coat protein, enabling the selection and evolution of antigen-specific antibodies through biopanning.

70

Publications

4.2K

Citations

363

Authors

113

Institutions

Publications per year

2017–2026

10

Parents

Publications

70

Assembly of combinatorial antibody libraries on phage surfaces: the gene III site.

Carlos F. Barbas, Angray S. Kang, Richard A. Lerner et al. · Proceedings of the National Academy of Sciences · 1991 · 1.2K citations

, , +17

A helper phage to improve single-chain antibody presentation in phage display

Susanne Rondot, Joachim Koch, Frank Breitling et al. · Nature Biotechnology · 2001 · 296 citations

, , +16

Selection of human antibody fragments by phage display

Carol M.Y. Lee, Niccolo Iorno, Frédéric Sierro et al. · Nature Protocols · 2007 · 264 citations

, , +14

A fully synthetic human Fab antibody library based on fixed VH/VL framework pairings with favorable biophysical properties

Thomas Tiller, Ingrid Schuster, Dorothée Deppe et al. · mAbs · 2013 · 205 citations · Full text

, , +17

Combinatorial immunoglobulin libraries on the surface of phage (Phabs): Rapid selection of antigen-specific fabs

Carlos F. Barbas, Richard A. Lerner · Methods · 1991 · 145 citations

, , +16

1–5 of 70

Authors

363

  1. MT
    Mark Tornetta

    New Frontier, United States

    5 publications · 169 citations

    5

    h-index

  2. PT
    Ping Tsui

    Stony Brook University, United States

    4 publications · 139 citations

    4

    h-index

  3. LJ
    Lisa J. Garrard

    University of East-West Medicine, United States

    3 publications · 219 citations

    3

    h-index

  4. SZ
    Stefan Zielonka

    Technische Universität Darmstadt, Germany

    3 publications · 61 citations

    3

    h-index

  5. RA
    Richard A. Lerner

    Scripps Research Institute, United States

    3 publications · 1.3K citations

    3

    h-index

1–5 of 363

Institutions

113

  1. Scripps Research Institute

    San Diego, United States

    7 h-index

    19 publications

    5.3K citations

  2. University of Pennsylvania

    Philadelphia, United States

    3 h-index

    4 publications

    62 citations

  3. University of Liège

    Liège, Belgium

    3 h-index

    9 publications

    442 citations

  4. Merck KGaA, Darmstadt (Germany)

    Darmstadt, Germany

    3 h-index

    23 publications

    483 citations

  5. Kangwon National University

    Chuncheon, South Korea

    3 h-index

    14 publications

    333 citations

  6. New Frontier

    Fallon, United States

    3 h-index

    11 publications

    315 citations

  7. Genesys (United States)

    Daly City, United States

    2 h-index

    4 publications

    449 citations

  8. Boston University

    Boston, United States

    2 h-index

    5 publications

    100 citations

1–8 of 113

Venues

  1. Journal of Immunological Methods

    8 publications · 261 citations

    8

    h-index

  2. Protein Engineering Design and Selection

    PEDS · 5 publications · 124 citations

    5

    h-index

  3. The Journal of Immunology

    JI · 4 publications · 123 citations

    4

    h-index

  4. Methods in molecular biology

    Book series · 4 publications · 51 citations

    4

    h-index

  5. PubMed

    Repository · 3 publications · 129 citations

    3

    h-index

1–5