Concepedia

F2 Similarity Testing

F2 Similarity Testing is a statistical method used in pharmaceutical equivalence assessment that quantifies the similarity between the dissolution profiles of a test and a reference drug product by calculating a model-independent metric based on the relative difference in their mean dissolution values across time points.

22

Publications

1.4K

Citations

81

Authors

36

Institutions

Publications per year

2017–2026

7

Variants

F2 MetricF2 Test

Parents

Publications

22

In Vitro Dissolution Profile Comparison—Statistics and Analysis of the Similarity Factor, f2

Vinod P. Shah, Yi Tsong, Pradeep Sathe et al. · Pharmaceutical Research · 1998 · 678 citations

, , +11

Model Comparisons and R 2

Richard Anderson‐Sprecher · The American Statistician · 1994 · 106 citations

, , +12

In vitro dissolution similarity factor (f2) and in vivo bioequivalence criteria, how and when do they match? Using a BCS class II drug as a simulation example

Feifan Xie, Shan Ji, Zeneng Cheng · European Journal of Pharmaceutical Sciences · 2014 · 99 citations

, , +16

Dissolution Profile Comparison Using Similarity Factor, f2

Vinod P. Shah, Yi Tsong, Pradeep Sathe et al. · Dissolution Technologies · 1999 · 62 citations

, , +7

Evaluation of dissolution profile similarity – Comparison between the f2, the multivariate statistical distance and the f2 bootstrapping methods

Paulo Paixão, Luís F. Gouveia, Nuno Silva et al. · European Journal of Pharmaceutics and Biopharmaceutics · 2016 · 53 citations

, , +10

1–5 of 22

Authors

81

  1. AG
    Alfredo García‐Arieta

    Agencia Española de Medicamentos y Productos Sanitarios, Spain

    3 publications · 88 citations

    3

    h-index

  2. JL
    Jen‐pei Liu

    National Health Research Institutes, Taiwan

    3 publications · 752 citations

    3

    h-index

  3. VP
    Vinod P. Shah

    Center for Drug Evaluation and Research, United States

    2 publications · 740 citations

    2

    h-index

  4. MG
    Marta González‐Álvarez

    Universitat de València, Spain

    2 publications · 70 citations

    2

    h-index

  5. MM
    Mi-Chia Ma

    National Cheng Kung University, Taiwan

    2 publications · 74 citations

    2

    h-index

1–5 of 81

Institutions

36

  1. National Cheng Kung University

    Tainan City, Taiwan

    3 h-index

    4 publications

    799 citations

  2. Universitat Politècnica de València

    Valencia, Spain

    2 h-index

    4 publications

    106 citations

  3. Universitat de València

    Valencia, Spain

    2 h-index

    4 publications

    106 citations

  4. Universitat de Miguel Hernández d'Elx

    Elche, Spain

    2 h-index

    13 publications

    455 citations

  5. Pfizer (United States)

    New York, United States

    1 h-index

    4 publications

    76 citations

  6. Universiti Sains Malaysia

    George Town, Malaysia

    1 h-index

    2 publications

    56 citations

  7. Shanghai University of Traditional Chinese Medicine

    Shanghai, China

    1 h-index

    3 publications

    51 citations

  8. Research Triangle Park Foundation

    Durham, United States

    1 h-index

    1 publications

    14 citations

1–8 of 36

Venues

  1. Dissolution Technologies

    3 publications · 97 citations

    3

    h-index

  2. Drug Development and Industrial Pharmacy

    3 publications · 76 citations

    3

    h-index

  3. European Journal of Pharmaceutical Sciences

    2 publications · 117 citations

    2

    h-index

  4. Journal of Biopharmaceutical Statistics

    JBS · 2 publications · 56 citations

    2

    h-index

  5. Pharmaceutics

    1 publications · 35 citations

    1

    h-index

1–5