Paulo Paixão

Low Buffer Capacity and Alternating Motility along the Human Gastrointestinal Tract: Implications for <i>in Vivo</i> Dissolution and Absorption of Ionizable Drugs

Bart Hens, Yasuhiro Tsume, Marival Bermejo et al. · Molecular Pharmaceutics · 2017 · 125 citations

Ibuprofen Tablet, Healthy Subjects, Gastrointestinal Pharmacology +22

Metabolism of primaquine by liver homogenate fractions

Luís Constantino, Paulo Paixão, Rui Moreira et al. · Experimental and Toxicologic Pathology · 1999 · 89 citations

Biochemistry, Liver Physiology, Liver Homogenate Fractions +6

Prediction of the human oral bioavailability by using in vitro and in silico drug related parameters in a physiologically based absorption model

Paulo Paixão, Luís F. Gouveia, José Morais · International Journal of Pharmaceutics · 2012 · 79 citations

Pharmacological Study, Medicine, Drug Purity +12

A Mechanistic Physiologically-Based Biopharmaceutics Modeling (PBBM) Approach to Assess the In Vivo Performance of an Orally Administered Drug Product: From IVIVC to IVIVP

Marival Bermejo, Bart Hens, Joseph Dickens et al. · Pharmaceutics · 2020 · 68 citations · Full text

Prediction of the in vitro permeability determined in Caco-2 cells by using artificial neural networks

Paulo Paixão, Luís F. Gouveia, José Morais · European Journal of Pharmaceutical Sciences · 2010 · 63 citations

Vitro Permeability, Caco-2 Cells, Engineering +14