Concepedia

Expression Noise Control

Expression Noise Control is a regulatory strategy that specifically modulates transcriptional variability in genetic circuits by engineering cis-regulatory elements to minimize stochastic fluctuations in gene expression while maintaining desired mean expression levels.

33

Publications

3.3K

Citations

121

Authors

59

Institutions

Publications per year

2017–2026

15

Variants

Gene Expression Noise Control

Parents

Publications

33

Control of Stochasticity in Eukaryotic Gene Expression

Jonathan M. Raser, Erin K. O’Shea · Science · 2004 · 1.5K citations · Full text

, , +17

Screening for noise in gene expression identifies drug synergies

Roy D. Dar, Nina N. Hosmane, Michelle R. Arkin et al. · Science · 2014 · 226 citations

, , +17

Evolution of chromosome organization driven by selection for reduced gene expression noise

Nizar N. Batada, Laurence D. Hurst · Nature Genetics · 2007 · 215 citations

, , +14

Tuning and controlling gene expression noise in synthetic gene networks

Kevin Murphy, Rhys Adams, Xiao Wang et al. · Nucleic Acids Research · 2010 · 149 citations · Full text

, , +17

Orthogonal control of expression mean and variance by epigenetic features at different genomic loci

Siddharth S. Dey, Jonathan E. Foley, Prajit Limsirichai et al. · Molecular Systems Biology · 2015 · 148 citations · Full text

, , +15

1–5 of 33

Authors

121

  1. AM
    Arvind Murugan

    University of Chicago, United States

    2 publications · 98 citations

    2

    h-index

  2. LS
    Leor S. Weinberger

    Gladstone Institutes, United States

    2 publications · 246 citations

    2

    h-index

  3. LD
    Laurence D. Hurst

    University of Bath, United Kingdom

    2 publications · 273 citations

    2

    h-index

  4. AS
    Abhyudai Singh

    University of Delaware, United States

    2 publications · 116 citations

    2

    h-index

  5. JM
    James M. Linton

    Howard Hughes Medical Institute, United States

    2 publications · 98 citations

    2

    h-index

1–5 of 121

Institutions

59

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    5 h-index

    6 publications

    3.4K citations

  2. Center for Systems Biology

    Boston, United States

    4 h-index

    8 publications

    716 citations

  3. University of California, San Francisco

    San Francisco, United States

    3 h-index

    7 publications

    576 citations

  4. California Institute of Technology

    Pasadena, United States

    3 h-index

    14 publications

    701 citations

  5. Weizmann Institute of Science

    Rehovot, Israel

    3 h-index

    8 publications

    932 citations

  6. Max Planck Institute for Terrestrial Microbiology

    Marburg, Germany

    2 h-index

    6 publications

    266 citations

  7. Gladstone Institutes

    San Francisco, United States

    2 h-index

    4 publications

    492 citations

  8. Harvard University

    Cambridge, United States

    2 h-index

    3 publications

    91 citations

1–8 of 59

Venues

  1. Nucleic Acids Research

    3 publications · 227 citations

    3

    h-index

  2. Nature Communications

    3 publications · 112 citations

    3

    h-index

  3. bioRxiv (Cold Spring Harbor Laboratory)

    Repository · 2 publications · 30 citations

    2

    h-index

  4. Molecular BioSystems

    2 publications · 67 citations

    2

    h-index

  5. Science

    2 publications · 1.7K citations

    2

    h-index

1–5