Expression Burden is a metabolic burden reduction strategy that specifically refers to the physiological cost imposed on a cell by the synthesis and maintenance of gene expression machinery, including transcription and translation processes, thereby diverting resources from growth and other essential functions.
5
Publications
767
Citations
15
Authors
6
Institutions
Publications per year
2017–2026
3
Parents
Publications
5
Quantifying cellular capacity identifies gene expression designs with reduced burden
Francesca Ceroni, Rhys Algar, Guy‐Bart Stan et al. · Nature Methods · 2015 · 534 citations
Cell-free prediction of protein expression costs for growing cells
Olivier Borkowski, Carlos Bricio, Michela Murgiano et al. · Nature Communications · 2018 · 120 citations · Full text
Trade-Offs in Biosensor Optimization for Dynamic Pathway Engineering
Babita K. Verma, Ahmad A. Mannan, Fuzhong Zhang et al. · ACS Synthetic Biology · 2021 · 31 citations · Full text
1–5 of 5
Authors
15
- GS
3
h-index
- TE
3
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- OB
2
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- CB
2
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- BK
1
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1–5 of 15
Institutions
6
Imperial College London
London, United Kingdom
3 h-index
15 publications
2.9K citations
University of Warwick
Coventry, United Kingdom
1 h-index
1 publications
31 citations
Indian Institute of Technology Delhi
New Delhi, India
1 h-index
2 publications
138 citations
Turing Institute
Glasgow, United Kingdom
1 h-index
1 publications
31 citations
Washington University in St. Louis
St Louis, United States
1 h-index
1 publications
31 citations
University of Edinburgh
Edinburgh, United Kingdom
1 h-index
2 publications
62 citations
1–6 of 6
Venues
- Nature Communications
1 publications · 120 citations
1
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- Biotechnology Letters
1 publications · 69 citations
1
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- bioRxiv (Cold Spring Harbor Laboratory)
Repository · 1 publications · 13 citations
1
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- Nature Methods
1 publications · 534 citations
1
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- ACS Synthetic Biology
1 publications · 31 citations
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