Concepedia

Expanded Genetic Codes

Expanded Genetic Codes is a methodological framework in synthetic biology that extends the standard genetic code by incorporating noncanonical amino acids through engineered tRNA-synthetase pairs, thereby enabling site-specific incorporation of novel chemical functionalities into proteins.

209

Publications

16.8K

Citations

852

Authors

279

Institutions

Publications per year

2017–2026

84

Parents

Publications

209

Expanding the Genetic Code of <i>Escherichia coli</i>

Lei Wang, Ansgar Brock, Brad Herberich et al. · Science · 2001 · 1.5K citations

, , +17

General Nature of the Genetic Code for Proteins

Francis Crick, Leslie Barnett, S. BRENNER et al. · Nature · 1961 · 1.4K citations

, , +14

Genomically Recoded Organisms Expand Biological Functions

Alexis J. Rovner, Daniel B. Goodman, Hans R. Aerni et al. · Science · 2013 · 884 citations · Full text

, , +17

An Expanded Eukaryotic Genetic Code

Jason W. Chin, T. Ashton Cropp, J. Christopher Anderson et al. · Science · 2003 · 830 citations

, , +17

A semi-synthetic organism with an expanded genetic alphabet

Denis A. Malyshev, Kirandeep Dhami, Thomas Lavergne et al. · Nature · 2014 · 621 citations · Full text

, , +14

1–5 of 209

Authors

852

  1. PG
    Peter G. Schultz

    Scripps Research Institute, United States

    14 publications · 4.4K citations

    13

    h-index

  2. JW
    Jason W. Chin

    MRC Laboratory of Molecular Biology, United Kingdom

    12 publications · 2.5K citations

    12

    h-index

  3. DS
    Dieter Söll

    Yale University, United States

    10 publications · 973 citations

    10

    h-index

  4. NB
    Nediljko Budiša

    Technische Universität Berlin, Germany

    10 publications · 533 citations

    10

    h-index

  5. KS
    Kensaku Sakamoto

    The University of Tokyo, Japan

    9 publications · 519 citations

    9

    h-index

1–5 of 852

Institutions

279

  1. Scripps Research Institute

    San Diego, United States

    18 h-index

    66 publications

    19.1K citations

  2. Yale University

    New Haven, United States

    15 h-index

    53 publications

    9.8K citations

  3. MRC Laboratory of Molecular Biology

    Cambridge, United Kingdom

    12 h-index

    35 publications

    11.2K citations

  4. Medical Research Council

    London, United Kingdom

    10 h-index

    29 publications

    10.1K citations

  5. Peking University

    Beijing, China

    10 h-index

    65 publications

    1.7K citations

  6. The University of Tokyo

    Tokyo, Japan

    9 h-index

    49 publications

    2.6K citations

  7. The University of Texas at Austin

    Austin, United States

    9 h-index

    45 publications

    2.7K citations

  8. Technische Universität Berlin

    Berlin, Germany

    8 h-index

    19 publications

    724 citations

1–8 of 279

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 14 publications · 1.4K citations

    14

    h-index

  2. Journal of the American Chemical Society

    JACS · 14 publications · 1.8K citations

    14

    h-index

  3. ACS Synthetic Biology

    10 publications · 252 citations

    10

    h-index

  4. Science

    10 publications · 4.3K citations

    10

    h-index

  5. Nucleic Acids Research

    8 publications · 305 citations

    8

    h-index

1–5