Concepedia

Exo1-dependent Resection

EXO1-Dependent Resection is a molecular mechanism of DNA end resection that belongs to the class of 5'→3' exonuclease-mediated resection pathways and is specifically characterized by its reliance on the exonuclease EXO1 to catalyze the stepwise degradation of the 5'-terminated DNA strand at double-strand breaks.

30

Publications

2.9K

Citations

146

Authors

55

Institutions

Publications per year

2017–2026

11

Parents

Publications

30

Bidirectional resection of DNA double-strand breaks by Mre11 and Exo1

Valérie Garcia, Sarah Phelps, Stephen Gray et al. · Nature · 2011 · 451 citations · Full text

, , +13

Mechanism of the ATP-dependent DNA end-resection machinery from Saccharomyces cerevisiae

Hengyao Niu, Woo-Hyun Chung, Zhu Zhu et al. · Nature · 2010 · 377 citations · Full text

, , +12

Ku prevents Exo1 and Sgs1‐dependent resection of DNA ends in the absence of a functional MRX complex or Sae2

Eleni P. Mimitou, Lorraine S. Symington · The EMBO Journal · 2010 · 307 citations · Full text

, , +7

A global view of meiotic double-strand break end resection

Eleni P. Mimitou, Shintaro Yamada, Scott Keeney · Science · 2017 · 199 citations

, , +17

Poly(ADP-ribose) polymerase-1 antagonizes DNA resection at double-strand breaks

Marie‐Christine Caron, Ajit Kumar Sharma, Julia O’Sullivan et al. · Nature Communications · 2019 · 183 citations · Full text

, , +17

1–5 of 30

Authors

146

  1. PS
    Patrick Sung

    Yale University, United States

    5 publications · 519 citations

    5

    h-index

  2. NT
    Nozomi Tomimatsu

    The University of Texas Southwestern Medical Center, United States

    3 publications · 232 citations

    3

    h-index

  3. BM
    Bipasha Mukherjee

    Sankara Nethralaya, India

    3 publications · 232 citations

    3

    h-index

  4. WW
    Weibin Wang

    Peking University, China

    3 publications · 96 citations

    3

    h-index

  5. SB
    Sandeep Burma

    The University of Texas Southwestern Medical Center, United States

    3 publications · 232 citations

    3

    h-index

1–5 of 146

Institutions

55

  1. Yale University

    New Haven, United States

    5 h-index

    29 publications

    4.1K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    3 h-index

    10 publications

    1K citations

  3. University of Milano-Bicocca

    Milan, Italy

    3 h-index

    18 publications

    626 citations

  4. The University of Texas at Austin

    Austin, United States

    3 h-index

    11 publications

    1.2K citations

  5. Howard Hughes Medical Institute

    Chevy Chase, United States

    3 h-index

    9 publications

    931 citations

  6. California Institute of Technology

    Pasadena, United States

    2 h-index

    2 publications

    136 citations

  7. Université Laval

    Québec, Canada

    2 h-index

    21 publications

    1.8K citations

  8. Washington University in St. Louis

    St Louis, United States

    2 h-index

    14 publications

    656 citations

1–8 of 55

Venues

  1. Nucleic Acids Research

    7 publications · 249 citations

    7

    h-index

  2. Nature Communications

    5 publications · 540 citations

    5

    h-index

  3. Journal of Biological Chemistry

    JBC · 3 publications · 102 citations

    3

    h-index

  4. The EMBO Journal

    3 publications · 425 citations

    3

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 2 publications · 235 citations

    2

    h-index

1–5