Concepedia

Epigenetic Target Validation

Epigenetic Target Validation is the systematic experimental and computational assessment of epigenetic regulators, marks, or loci to establish their causal role in specific biological functions or disease phenotypes, distinguishing it from related epigenomic analyses by its focus on functional causality and therapeutic relevance.

8

Publications

284

Citations

107

Authors

45

Institutions

Publications per year

2017–2026

3

Parents

Publications

8

Experimental validation of candidate schizophrenia gene ZNF804A as target for hsa-miR-137

Albert H. Kim, Erin K. Parker, Vernell Williamson et al. · Schizophrenia Research · 2012 · 90 citations

, , +12

Small-Molecule Ligands of Methyl-Lysine Binding Proteins: Optimization of Selectivity for L3MBTL3

Lindsey I. James, Victoria Korboukh, Liubov Krichevsky et al. · Journal of Medicinal Chemistry · 2013 · 65 citations · Full text

, , +14

Observed bromodomain flexibility reveals histone peptide- and small molecule ligand-compatible forms of ATAD2

G. Poncet-Montange, Yanai Zhan, Jennifer Bardenhagen et al. · Biochemical Journal · 2014 · 37 citations

, , +17

Identification of bromodomain-containing protein-4 as a novel marker and epigenetic target in mast cell leukemia

Ghaith Wedeh, Sabine Cerny‐Reiterer, Gregor Eisenwort et al. · Leukemia · 2015 · 22 citations · Full text

, , +15

Virtual screening in small molecule discovery for epigenetic targets

Guo‐Bo Li, Lingling Yang, Yiming Yuan et al. · Methods · 2014 · 21 citations

, , +16

1–5 of 8

Authors

107

  1. JJ
    Jian Jin

    Icahn School of Medicine at Mount Sinai, United States

    2 publications · 78 citations

    2

    h-index

  2. LY
    Lingling Yang

    Sichuan University, China

    1 publications · 21 citations

    1

    h-index

  3. XS
    Xi Shi

    Broad Institute, United States

    1 publications · 37 citations

    1

    h-index

  4. FA
    Franco Aversa

    University of Perugia, Italy

    1 publications · 13 citations

    1

    h-index

  5. HH
    Harald Herrmann

    Medical University of Vienna, Austria

    1 publications · 22 citations

    1

    h-index

1–5 of 107

Institutions

45

  1. Ludwig-Maximilians-Universität München

    Munich, Germany

    2 h-index

    4 publications

    70 citations

  2. Harvard University

    Cambridge, United States

    2 h-index

    7 publications

    100 citations

  3. Dana-Farber Cancer Institute

    Boston, United States

    2 h-index

    7 publications

    100 citations

  4. University of Toronto

    Toronto, Canada

    1 h-index

    2 publications

    130 citations

  5. Shanghai Jiao Tong University

    Shanghai, China

    1 h-index

    3 publications

    60 citations

  6. University of Perugia

    Perugia, Italy

    1 h-index

    4 publications

    52 citations

  7. Medical University of Vienna

    Vienna, Austria

    1 h-index

    11 publications

    242 citations

  8. Université Paris-Saclay

    Gif-sur-Yvette, France

    1 h-index

    1 publications

    16 citations

1–8 of 45

Venues

  1. Schizophrenia Research

    1 publications · 90 citations

    1

    h-index

  2. Cell Death and Disease

    1 publications · 13 citations

    1

    h-index

  3. Methods

    1 publications · 21 citations

    1

    h-index

  4. Biochemical Journal

    BJ · 1 publications · 37 citations

    1

    h-index

  5. Journal of Medicinal Chemistry

    1 publications · 65 citations

    1

    h-index

1–5